6-Gingerol inhibits ROS and iNOS through the suppression of PKC-α and NF-κB pathways in lipopolysaccharide-stimulated mouse macrophages

TY Lee, KC Lee, SY Chen, HH Chang - Biochemical and biophysical …, 2009 - Elsevier
Inflammation is involved in numerous diseases, including chronic inflammatory diseases
and the development of cancer. Many plants possess a variety of biological activities …

Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264. 7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway

KC Lee, HH Chang, YH Chung, TY Lee - Journal of ethnopharmacology, 2011 - Elsevier
Ethnopharmacological significance Inflammation is involved in numerous diseases, such as
chronic inflammatory disease and cancer. Many plant products exhibit useful biological …

[HTML][HTML] Positive effect of curcumin on inflammation and mitochondrial dysfunction in obese mice with liver steatosis

JJ Kuo, HH Chang, TH Tsai… - … journal of molecular …, 2012 - spandidos-publications.com
Obesity contributes to the increased risk of liver-related morbidity and mortality. The
accumulation of macrophages in adipose tissue in an inflammatory state is a hallmark of …

[HTML][HTML] Modulation of gut microbiota combined with upregulation of intestinal tight junction explains anti-inflammatory effect of corylin on colitis-associated cancer in …

ZY Chang, HM Liu, YL Leu, CH Hsu… - International journal of …, 2022 - mdpi.com
Inflammatory bowel disease (IBD) involves chronic inflammation, loss of epithelial integrity,
and gastrointestinal microbiota dysbiosis, resulting in the development of a colon cancer …

The effect of auricular acupuncture in obese women: a randomized controlled trial

CH Hsu, CJ Wang, KC Hwang, TY Lee… - Journal of Women's …, 2009 - liebertpub.com
Background: The aims of this randomized study are to examine the effect of auricular
acupuncture on obese women and to explore the relationship between the effect of auricular …

Herb medicine Yin-Chen-Hao-Tang ameliorates hepatic fibrosis in bile duct ligation rats

TY Lee, HH Chang, JH Chen, ML Hsueh… - Journal of …, 2007 - Elsevier
The accumulation of hydrophilic bile acids in the liver is considered to play a pivotal role in
the induction of hepatic injury. Yin-Chen-Hao-Tang (YCHT) decoction is an aqueous extract …

[HTML][HTML] Ursodeoxycholic acid regulates hepatic energy homeostasis and white adipose tissue macrophages polarization in leptin-deficiency obese mice

YS Chen, HM Liu, TY Lee - Cells, 2019 - mdpi.com
Obesity has been shown to play a role in the pathogenesis of several forms of metabolic
syndrome, including non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes …

[HTML][HTML] Curcumin ameliorates mitochondrial dysfunction associated with inhibition of gluconeogenesis in free fatty acid-mediated hepatic lipoapoptosis

JJ Kuo, HH Chang, TH Tsai… - … Journal of Molecular …, 2012 - spandidos-publications.com
Insulin resistance occurs in almost all patients with non-alcoholic fatty liver disease
(NAFLD), and mitochondrial dysfunction likely plays a pivotal role in the progression of fatty …

Protective mechanism of salvia miltiorrhiza on carbon tetrachloride-induced acute hepatotoxicity in rats

TY Lee, LM Mai, GJ Wang, JH Chiu, YL Lin… - Journal of …, 2003 - jstage.jst.go.jp
The purpose of this study was to investigate the possible mechanisms of Salvia miltiorrhiza
(Sm) in carbon tetrachloride (CCl4)-induced acute hepatotoxicity in rats. Male Wistar rats …

Long-term administration of Salvia miltiorrhiza ameliorates carbon tetrachloride-induced hepatic fibrosis in rats

TY Lee, GJ Wang, JH Chiu… - Journal of Pharmacy and …, 2003 - academic.oup.com
Carbon tetrachloride (CCl4) is metabolized by cytochrome P450 to form a reactive
trichloromethyl radical that triggers a chain of lipid peroxidation. These changes lead to cell …