[HTML][HTML] Evidence-based clinical practice guidelines for inflammatory bowel disease 2020

H Nakase, M Uchino, S Shinzaki, M Matsuura… - Journal of …, 2021 - Springer
Inflammatory bowel disease (IBD) is a general term for chronic or remitting/relapsing
inflammatory diseases of the intestinal tract and generally refers to ulcerative colitis (UC) …

[HTML][HTML] Inflammatory bowel disease and sarcopenia: its mechanism and clinical importance

H Nishikawa, S Nakamura, T Miyazaki… - Journal of Clinical …, 2021 - mdpi.com
Malnutrition is a major contributor to muscle loss and muscle dysfunction, known as
sarcopenia. Malnutrition is common in patients with inflammatory bowel disease (IBD). IBD …

Screening tools for sarcopenia

H Nishikawa, A Asai, S Fukunishi, T Takeuchi, M Goto… - in vivo, 2021 - iv.iiarjournals.org
The elderly people are characterized by multiple comorbidities, dementia, and are at risk of
developing sarcopenia and frailty. Sarcopenia is defined by loss of muscle mass and muscle …

Multicenter analysis of fecal microbiota profiles in Japanese patients with Crohn's disease

A Andoh, H Kuzuoka, T Tsujikawa, S Nakamura… - Journal of …, 2012 - Springer
Background We analyzed the fecal microbiota profiles of patients with Crohn's disease (CD)
at 4 inflammatory bowel disease (IBD) centers located in different districts in Japan. Methods …

Differential expression of mucosal addressin cell adhesion molecule‐1 (MAdCAM‐1) in ulcerative colitis and Crohn's disease

S Arihiro, H Ohtani, M Suzuki, M Murata… - Pathology …, 2002 - Wiley Online Library
Mucosal addressin cell adhesion molecule‐1 (MAdCAM‐1) is selectively expressed in the
endothelial cells of intestinal mucosa and gut‐associated lymphoid tissue (GALT) …

Scheduled infliximab monotherapy to prevent recurrence of Crohn's disease following ileocolic or ileal resection: a 3-year prospective randomized open trial

K Yoshida, K Fukunaga, H Ikeuchi… - Inflammatory bowel …, 2012 - academic.oup.com
Background Infliximab (IFX) is effective for remission induction and maintenance of Crohn's
disease (CD). This trial assessed the efficacy of scheduled maintenance IFX monotherapy to …

GC/MS-based profiling of amino acids and TCA cycle-related molecules in ulcerative colitis

M Ooi, S Nishiumi, T Yoshie, Y Shiomi, M Kohashi… - Inflammation …, 2011 - Springer
Objective The roles that amino acids play in immunity and inflammation are well defined,
and the relationship between inflammatory bowel disease (IBD) and certain amino acids has …

[HTML][HTML] Generation of orthotopically functional salivary gland from embryonic stem cells

J Tanaka, M Ogawa, H Hojo, Y Kawashima… - Nature …, 2018 - nature.com
Organoids generated from pluripotent stem cells are used in the development of organ
replacement regenerative therapy by recapitulating the process of organogenesis. These …

An increase in LRRK2 suppresses autophagy and enhances Dectin-1–induced immunity in a mouse model of colitis

T Takagawa, A Kitani, I Fuss, B Levine… - Science translational …, 2018 - science.org
The LRRK2/MUC19 gene region constitutes a high-risk genetic locus for the occurrence of
both inflammatory bowel diseases (IBDs) and Parkinson's disease. We show that dendritic …

[HTML][HTML] NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory …

Y Kakuta, Y Kawai, D Okamoto, T Takagawa… - Journal of …, 2018 - Springer
Background Despite NUDT15 variants showing significant association with thiopurine-
induced adverse events (AEs) in Asians, it remains unclear which variants of NUDT15 or …