Ions and water transported across the endothelium lining the blood–brain barrier contribute
to the fluid secreted into the brain and are important in maintaining appropriate volume and …

Introduction Data from clinical trials indicate that direct oral anticoagulants (DOACs) are
noninferior and safer than conventional therapy (low-molecular-weight heparin followed by …

Aims: As many cases of atrial fibrillation (AF) are asymptomatic, patients often remain
undiagnosed until complications (eg stroke) manifest. Risk-prediction algorithms may help to …

Background Atrial fibrillation (AF) burden on patients and healthcare systems warrants
innovative strategies for screening asymptomatic individuals. Objective We sought to …

Objective To conduct a systematic review and network meta-analysis of real-world evidence
comparing adherence, persistence, cost, and utilization between oral anticoagulant (OAC) in …

Ischemia–reperfusion leads to increased levels at the blood–brain barrier of the multidrug
efflux transporter, P-glycoprotein that provides protection to the brain by limiting access of …

Aim Screening for non-valvular atrial fibrillation (NVAF) is key in identifying patients with
undiagnosed disease who may be eligible for anticoagulation therapy. Understanding the …

Background Health state (HS) utility values for patients with acute myeloid leukemia (AML),
a hematological malignancy, are not available in the United Kingdom (UK). This study aims …

Simple Summary Venous thromboembolism (VTE) is a common and often fatal complication
in cancer patients. The initial treatment for VTE in cancer patients is typically low molecular …

Aim: To evaluate the comparative efficacy and safety of gemtuzumab ozogamicin+
daunorubicin-cytarabine (GO+ DA) versus common induction therapies for newly diagnosed …