The role of thiopurines in reducing the need for surgical resection in Crohn's disease: a systematic review and meta-analysis
S Chatu, V Subramanian, S Saxena… - Official journal of the …, 2014 - journals.lww.com
OBJECTIVES: The thiopurine (TP) analogs azathioprine and mercaptopurine have proven
efficacy in inducing and maintaining clinical remission in Crohn's disease (CD). Their impact …
efficacy in inducing and maintaining clinical remission in Crohn's disease (CD). Their impact …
Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD
Objective Delayed second dose SARS-CoV-2 vaccination trades maximal effectiveness for a
lower level of immunity across more of the population. We investigated whether patients with …
lower level of immunity across more of the population. We investigated whether patients with …
[HTML][HTML] Diagnostic imaging and radiation exposure in inflammatory bowel disease
N Zakeri, RCG Pollok - World Journal of Gastroenterology, 2016 - ncbi.nlm.nih.gov
Diagnostic imaging plays a key role in the diagnosis and management of inflammatory
bowel disease (IBD). However due to the relapsing nature of IBD, there is growing concern …
bowel disease (IBD). However due to the relapsing nature of IBD, there is growing concern …
Preoperative steroid use and risk of postoperative complications in patients with inflammatory bowel disease undergoing abdominal surgery
V Subramanian, S Saxena, JY Kang… - Official journal of the …, 2008 - journals.lww.com
Preoperative Steroid Use and Risk of Postoperative Complicat... : Official journal of the American
College of Gastroenterology | ACG Preoperative Steroid Use and Risk of Postoperative …
College of Gastroenterology | ACG Preoperative Steroid Use and Risk of Postoperative …
Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab
NA Kennedy, JR Goodhand, C Bewshea, R Nice… - Gut, 2021 - gut.bmj.com
Objective Antitumour necrosis factor (anti-TNF) drugs impair protective immunity following
pneumococcal, influenza and viral hepatitis vaccination and increase the risk of serious …
pneumococcal, influenza and viral hepatitis vaccination and increase the risk of serious …
Association of genetic variants in NUDT15 with thiopurine-induced myelosuppression in patients with inflammatory bowel disease
Importance Use of thiopurines may be limited by myelosuppression. TPMTpharmacogenetic
testing identifies only 25% of at-risk patients of European ancestry. Among patients of East …
testing identifies only 25% of at-risk patients of European ancestry. Among patients of East …
Interferon gamma induces enterocyte resistance against infection by the intracellular pathogen Cryptosporidium parvum
Background and Aims: Interferon (IFN)-γ plays an important role in the immunologic control
of infection by the protozoan enteropathogen Cryptosporidium parvum. We tested the …
of infection by the protozoan enteropathogen Cryptosporidium parvum. We tested the …
The role of cytokines in the pathogenesis of Cryptosporidium infection
IS Lean, V McDonald, RCG Pollok - Current Opinion in Infectious …, 2002 - journals.lww.com
First described in 1912, the importance of the coccidian parasite Cryptosporidium parvum as
an enteropathogen in humans was not recognized until the early 1980s, when it was found …
an enteropathogen in humans was not recognized until the early 1980s, when it was found …
Vaccine escape, increased breakthrough and reinfection in infliximab-treated patients with IBD during the Omicron wave of the SARS-CoV-2 pandemic
Objective Antitumour necrosis factor (TNF) drugs impair serological responses following
SARS-CoV-2 vaccination. We sought to assess if a third dose of a messenger RNA (mRNA) …
SARS-CoV-2 vaccination. We sought to assess if a third dose of a messenger RNA (mRNA) …
Mannose-binding lectin is a component of innate mucosal defense against Cryptosporidium parvum in AIDS
P Kelly, DL Jack, A Naeem, B Mandanda, RCG Pollok… - Gastroenterology, 2000 - Elsevier
Background & Aims: Nonimmune mechanisms of mucosal defense seem to be biologically
important and might explain the observed variability in the course of enteric infection in …
important and might explain the observed variability in the course of enteric infection in …