Abstract Chicago Classification v4. 0 (CCv4. 0) is the updated classification scheme for
esophageal motility disorders using metrics from high‐resolution manometry (HRM). Fifty …

Background & Aims Over the last decade, clinical experiences and research studies raised
concerns regarding use of proton pump inhibitors (PPIs) as part of the diagnostic strategy for …

Achalasia is a primary motor disorder of the esophagus characterized by insufficient lower
esophageal sphincter relaxation and loss of esophageal peristalsis. This results in patients' …

The American Gastroenterological Association (AGA) Institute Medical Position Panel
consisted of the authors of the technical review, a community-based gastroenterologist …

BACKGROUND & AIMS: Acid and pepsin are known to cause esophagitis. However, the
role of duodenogastroesophageal reflux (DGER) in producing esophageal mucosal injury …

Abstract Background/Aims: Several reports suggest that duodenogastroesophageal reflux
may produce esophagitis, Barrett's esophagus, and esophageal adenocarcinoma. The …

Idiopathic achalasia is an inflammatory disease of unknown etiology characterized by
esophageal aperistalsis and failure of LES relaxation due to loss of inhibitory nitrinergic …

Safety issues associated with proton pump inhibitors (PPIs) have recently attracted
widespread media and lay attention. Gastroenterologists are frequently asked about the …

1. Demonstrate an understanding of the natural history and manifestations of reflux disease
2. Evaluate the role of diagnostic testing such as endoscopy, esophageal manometry …

Gastroesophageal reflux disease (GERD) has been associated increasingly with ear, nose,
and throat (ENT) signs and symptoms. However, the cause and effect relationship between …