Clinical features and genetic predisposition to hereditary nonmedullary thyroid cancer

MR Vriens, I Suh, W Moses, E Kebebew - Thyroid, 2009 - liebertpub.com
Background: Approximately 5% of the nonmedullary thyroid cancers are hereditary.
Hereditary nonmedullary thyroid cancer may occur as a minor component of familial cancer …

The optimal surgical treatment for primary hyperparathyroidism in MEN1 patients: a systematic review

JMJ Schreinemakers, CRC Pieterman… - World journal of …, 2011 - Wiley Online Library
Background The optimal surgical approach for patients with primary hyperparathyroidism
(pHPT) and multiple endocrine neoplasia 1 (MEN1) is controversial. We sought to determine …

[HTML][HTML] Use of PET tracers for parathyroid localization: a systematic review and meta-analysis

WP Kluijfhout, JD Pasternak, FT Drake… - … archives of surgery, 2016 - Springer
Purpose The great spatial and temporal resolution of positron emission tomography might
provide the answer for patients with primary hyperparathyroidism (pHPT) and non-localized …

Clinical spectrum of pheochromocytoma

MA Guerrero, JMJ Schreinemakers… - Journal of the …, 2009 - journals.lww.com
BACKGROUND: Pheochromocytomas vary in presentation, tumor size, and in
catecholamine production. Whether pheochromocytoma size correlates with hormone …

[HTML][HTML] Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN …

RF De Wilde, CM Heaphy, A Maitra, AK Meeker… - Modern …, 2012 - nature.com
Approximately 45% of sporadic well-differentiated pancreatic neuroendocrine tumors harbor
mutations in either ATRX (alpha thalassemia/mental retardation X-linked) or DAXX (death …

[HTML][HTML] Perioperative SARS-CoV-2 infections increase mortality, pulmonary complications, and thromboembolic events: a Dutch, multicenter, matched-cohort clinical …

PKC Jonker, WY Van der Plas, PJ Steinkamp… - Surgery, 2021 - Elsevier
Background A direct comparison of severe acute respiratory syndrome coronavirus 2
positive patients with a severe acute respiratory syndrome coronavirus 2 negative control …

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors

P Cejas, Y Drier, KMA Dreijerink, LAA Brosens… - Nature medicine, 2019 - nature.com
Most pancreatic neuroendocrine tumors (PNETs) do not produce excess hormones and are
therefore considered 'non-functional',–. As clinical behaviors vary widely and distant …

Pheochromocytoma crisis is not a surgical emergency

A Scholten, RM Cisco, MR Vriens… - The Journal of …, 2013 - academic.oup.com
Context: Pheochromocytoma crisis is a feared and potentially lethal complication of
pheochromocytoma. Objective: We sought to determine the best treatment strategy for …

[HTML][HTML] MEN1 redefined, a clinical comparison of mutation-positive and mutation-negative patients

JM De Laat, RB van der Luijt, CRC Pieterman… - BMC medicine, 2016 - Springer
Abstract Background Multiple Endocrine Neoplasia type 1 (MEN1) is diagnosed when two
out of the three primary MEN1-associated endocrine tumors occur in a patient. Up to 10 …

Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 …

WM Hackeng, LAA Brosens, JY Kim, R O'Sullivan… - Gut, 2022 - gut.bmj.com
Objective Recent studies have found aristaless-related homeobox gene (ARX)/pancreatic
and duodenal homeobox 1 (PDX1), alpha-thalassemia/mental retardation X-linked …