Background Chronic kidney disease (CKD) is a frequent, under-recognized condition and a
risk factor for renal failure and cardiovascular disease. Increasing evidence connects non …

Since the publication of the guidelines for the assessment and management of non alcoholic
fatty liver disease (NAFLD) by the Asia–Pacific Working Party on NAFLD in 2007, 1 our …

How to assess efficacy of interventions. In clinical practice, and particularly among those
who appear to have mild liver disease, it may be sufficient to note changes (normalization) of …

Background: The frequent association of nonalcoholic fatty liver disease with components of
the metabolic syndrome such as obesity, hyperglycemia, dyslipidemia, and hypertension is …

AIM We evaluated the association among the metabolic syndrome, visceral fat
accumulation, and the severity of fatty liver with a new scoring system of ultrasonographic …

The transcription factor Foxp3 is essential for the development of regulatory T (Treg) cells,
yet its expression is insufficient for establishing the Treg cell lineage. Here we showed that …

AIM: To clarify whether nonalcoholic fatty liver disease (NAFLD) increases the risk of
cardiovascular disease. METHODS: We carried out a prospective observational study with a …

CD4+ T cells that express the forkhead box P3 (FOXP3) transcription factor function as
regulatory T (Treg) cells and hinder effective immune responses against cancer cells …

In the FANTOM5 project, transcription initiation events across the human and mouse
genomes were mapped at a single base-pair resolution and their frequencies were …

Immunological tolerance to self requires naturally occurring regulatory T (Treg) cells. Yet
how they stably control autoimmune T cells remains obscure. Here, we show that Treg cells …