User profiles for "author:Kate Plehhova"

Kate Plehhova

Global Medical Affairs Manager - Reckitt
Verified email at reckitt.com
Cited by 20

Understanding the patient PPI journey: results of a survey on PPI treatment initiation and patient experience

K Plehhova, N Paquette, J Gould… - Journal of Primary Care …, 2022 - journals.sagepub.com
Introduction: Proton pump inhibitors (PPIs) used in the management of gastro-esophageal
reflux disease (GORD) are among the most frequently prescribed classes of drug worldwide …

[HTML][HTML] Topical Alginate Protection against Pepsin-Mediated Esophageal Damage: E-Cadherin Proteolysis and Matrix Metalloproteinase Induction

TL Samuels, S Blaine-Sauer, K Yan… - International Journal of …, 2023 - mdpi.com
Epithelial barrier dysfunction is a hallmark of gastroesophageal reflux disease (GERD)
related to symptom origination, inflammatory remodeling and carcinogenesis. Alginate …

Alginates for protection against pepsin‐acid induced aerodigestive epithelial barrier disruption

TL Samuels, K Yan, N Patel, K Plehhova… - The …, 2022 - Wiley Online Library
Objective Gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) are
chronic conditions caused by backflow of gastric and duodenal contents into the esophagus …

[HTML][HTML] Randomised clinical trial: the use of alginates during preinvestigation proton pump inhibitor wash-out and their impact on compliance and symptom burden

A Vales, C Coyle, K Plehhova… - BMJ Open …, 2023 - bmjopengastro.bmj.com
Background/aims Investigation of gastro-oesophageal reflux disease is usually performed
off proton pump inhibitors (PPIs). This can exacerbate symptoms, potentially impacting …

Prescribing Patterns of Proton Pump Inhibitors in Germany: A Retrospective Study Including 472 146 Patients

K Plehhova, M Haering, J Wray… - Journal of Primary …, 2023 - journals.sagepub.com
The aims of this study were to analyze proton pump inhibitor (PPI) users in Germany,
defining and classifying them in terms of treatment appropriateness, and to analyze the PPI …

Proton Pump Inhibitors in Germany: Status Quo of a Growing Market

K Plehhova, M Häring, J Wray… - Health Services …, 2024 - journals.sagepub.com
Introduction The volume of prescriptions for proton pump inhibitors (PPIs) remains high,
although the literature increasingly points to excessive prescribing in relation to guideline …

P143 Gaviscon double action protects against acid-induced increases in oesophageal mucosal permeability ex vivo

T Leech, A Ustaoglu, C Lee, K Plehhova, F McLaughlin… - 2023 - gut.bmj.com
Introduction Gastro-oesophageal reflux disease (GORD) is characterised by symptoms
(most commonly heartburn) caused by exposure of the oesophageal mucosa to gastric …

[CITATION][C] EP1116: THE USE OF ALGINATES DURING PRE-INVESTIGATION PROTON PUMP INHIBITOR WASHOUT: IMPACT ON COMPLIANCE AND SYMPTOM …

A Vales, C Coyle, K Plehhova, N Patel, A Hobson… - Gastroenterology, 2022 - Elsevier