Background Serum globulin is an inflammation marker. To date, no evidence regarding the
association between serum globulin and disease activity in patients with ulcerative colitis …

Hepatitis B vaccine induces the production of antibodies against hepatitis B surface antigen
(anti-HBs) and prevents hepatitis B virus (HBV) infection. However, 5–10% of individuals …

Background Mucosal healing (MH) has been indicated as the therapeutic goal for ulcerative
colitis (UC). Platelet count is known as an inflammation evaluation. However, the association …

METHODS: Study subjects consisted of 272 Japanese patients with UC. Monocyte counts
were taken in the morning after overnight fasting. Monocyte count was divided into tertiles …

Background A simple serum biomarker for clinical outcome in patients with ulcerative colitis
(UC) remains an unmet need. Some studies have shown an association between C-reactive …

Objective Serum albumin is used as a marker of acute inflammation. Several studies have
addressed the association between serum albumin and clinical outcome in patients with …

Double-stranded RNA-activated protein kinase R (PKR) is highly expressed in colorectal
cancer (CRC). However, the role of PKR in CRC remains unclear. The aim of this study was …

Purpose Bilirubin is known to have antioxidant effects. Several pieces of evidence regarding
association between serum bilirubin and UC exist. Three studies found that serum bilirubin …

Aim: Age is a risk factor for constipation. Constipation is common in patients with ulcerative
colitis (UC) and has been positively associated with disease activity, but evidence is limited …

Restless legs syndrome (RLS) is a common sleep disorder in the Western population. The
prevalence of restless legs syndrome in the Japanese population is 4.6%. Inflammatory …