Serotonin type 3 (5-HT3) receptors are pentameric ion channels belonging to the
superfamily of Cys-loop receptors. Receptor activation either leads to fast excitatory …

Diarrhea predominant irritable bowel syndrome (IBS-D) is a complex disorder related to
dysfunctions in the serotonergic system. As cis-regulatory variants can play a role in the …

Within the family of serotonin receptors, the 5-hydroxytryptamine-3 (5-HT3) receptor is the
only ligand-gated ion channel. It is composed of five subunits, of which the 5-HT3A and 5 …

Oxymetazoline and xylometazoline are both used as nasal mucosa decongesting α‐
adrenoceptor agonists during a common cold. However, it is largely unknown which of the …

Although five 5-hydroxytryptamine type 3 (5-HT3) subunits (A–E) have been cloned,
knowledge on the regulation of their assembly is limited. RIC-3 has been identified as a …

Objectives The 5-hydroxytryptamine-3 (5-HT 3) receptor, a ligand-gated ion channel, is
known to be involved in gut motility and peristalsis, the mediation of pain and psychiatric …

Objective We assessed whether the bicarbonate-rich mineral water Staatl. Fachingen STILL
is superior over conventional mineral water in relieving heartburn. Design Multicentre …

BACKGROUND Single-nucleotide polymorphisms (SNPs) of the serotonin type 3 receptor
subunit (HTR3) genes have been associated with psychosomatic symptoms, but it is not …

The classical electrophysiological method to measure the function of the 5-
hydroxytryptamine (serotonin) type 3 (5-HT3) receptor, a cation-permeable ligand-gated ion …

The aim of this study was to analyze functional properties of the naturally occurring C23S
variant of the human 5-HT2C receptor. In HEK293 cells transiently expressing the unedited …