Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: a prospective multicentre cohort study (GCEP)

JWJ Lee, F Zhu, S Srivastava, SKK Tsao, C Khor… - Gut, 2022 - gut.bmj.com
Objective To investigate the incidence of gastric cancer (GC) attributed to gastric intestinal
metaplasia (IM), and validate the Operative Link on Gastric Intestinal Metaplasia (OLGIM) for …

[HTML][HTML] Infection with pathogenic Blastocystis ST7 is associated with decreased bacterial diversity and altered gut microbiome profiles in diarrheal patients

L Deng, JWJ Lee, KSW Tan - Parasites & Vectors, 2022 - Springer
Background Blastocystis is a common protistan parasite inhabiting the gastrointestinal tract
of humans and animals. While there are increasing reports characterizing the associations …

Two vs one forward view examination of right colon on adenoma detection: an international multicenter randomized trial

RSY Tang, JWJ Lee, LC Chang, DEH Ong… - Clinical …, 2022 - Elsevier
Background & Aims Second forward view (SFV) examination of the right colon (RC) in
colonoscopy was suggested to improve the adenoma detection rate (ADR), but multicenter …

Sorafenib induces growth suppression in mouse models of gastrointestinal stromal tumor

H Huynh, JWJ Lee, PKH Chow, VC Ngo, GB Lew… - Molecular cancer …, 2009 - AACR
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the
gastrointestinal tract. Current therapeutic options include surgery and targeted molecular …

[HTML][HTML] Prevalence and molecular subtyping of Blastocystis in patients with Clostridium difficile infection, Singapore

L Deng, H Tay, G Peng, JWJ Lee, KSW Tan - Parasites & Vectors, 2021 - Springer
Background Blastocystis is a common anaerobic colonic protist in humans with controversial
pathogenicity. Clostridium difficile (C. difficile) is the commonest cause of infectious diarrhea …

Comparing artificial intelligence to humans for endoscopic diagnosis of gastric neoplasia: An external validation study

SXZ Quek, JWJ Lee, Z Feng, MM Soh… - Journal of …, 2023 - Wiley Online Library
Objectives Artificial intelligence (AI) uses deep learning functionalities that may enhance the
detection of early gastric cancer during endoscopy. An AI‐based endoscopic system for …

Advanced endoscopic imaging in gastric neoplasia and preneoplasia

JWJ Lee, LG Lim, KG Yeoh… - BMJ open …, 2017 - bmjopengastro.bmj.com
Conventional white light endoscopy remains the current standard in routine clinical practice
for early detection of gastric cancer. However, it may not accurately diagnose preneoplastic …

[HTML][HTML] Microbiome and human host interactions and their implications on human health

J Leo, CW Chong, AY Pribowo, R Sutejo… - Frontiers in …, 2023 - frontiersin.org
In this specialized Research Topics collection of Frontiers in Microbiology, we highlight key
research papers on the microbiome and their impact on a wide variety of health conditions …

Ciprofloxacin plus gemcitabine-based chemotherapy in patients with metastatic pancreatic ductal adenocarcinoma: A pilot study of microbiome manipulation.

SW Cheo, JWJ Lee, RJ Walsh, R Sundar, JRE Choo… - 2022 - ascopubs.org
570 Background: Gemcitabine-based chemotherapy is an approved therapy for treatment-
naïve metastatic pancreatic ductal adenocarcinoma (PDAC). Inherent resistance to …

[CITATION][C] Tu1296 prospective cohort study of gastric intestinal metaplasia progression and risk factors

JWJ Lee, CJ Koh, LG Lim, KY Ho, C Chung-King… - Gastroenterology, 2016 - Elsevier