Background and aims: Hepatitis E virus (HEV) infection is a significant public health problem
that afflicts almost 20 million individuals annually and causes acute liver injury in 3.5 million …

Various types of bias and confounding have been described in the biomedical literature that
can affect a study before, during, or after the intervention has been delivered. The peer …

Case reports and case series are uncontrolled study designs known for increased risk of
bias but have profoundly influenced the medical literature and continue to advance our …

Background and Aims Endoscopic transluminal drainage of symptomatic walled-off necrosis
(WON) is a good management option, although the optimal choice of drainage site stent is …

Background Endoscopic sleeve gastroplasty (ESG) is an endolumenal, organ-sparing
therapy for obesity, with wide global adoption. We aimed to explore the efficacy and safety of …

Background Endoscopic sleeve gastroplasty (ESG) is a technique for managing mild to
moderately obese patients. We aimed to evaluate the long-term outcomes, reproducibility …

There are limited data on the natural history of primary sclerosing cholangitis (PSC) in
children. We aimed to describe the disease characteristics and long‐term outcomes of …

Background & Aims Obese patients with nonalcoholic steatohepatitis (NASH) are at risk for
cirrhosis if significant weight loss is not achieved. The single fluid-filled intragastric balloon …

Background and Aims Symptomatic pancreatic walled-off necrosis (WON) may be managed
by endoscopic transmural drainage and endoscopic transmural necrosectomy, with stent …

Background & Aims Transient elastography (TE) is a noninvasive technique used to
measure liver stiffness to estimate the severity of fibrosis. The range of liver stiffness …