Background The prognosis of patients with gastroesophageal adenocarcinoma is poor.
There is conflicting evidence regarding effects of preoperative chemotherapy on survival …

Over the past years unrelated cord blood transplant (UCBT) has emerged as an effective
alternative to unrelated donor blood and marrow transplantation. However, despite several …

Purpose The primary treatment modality for patients with carcinoma of the esophagus or
gastroesophageal junction has been surgery, although primary radiation therapy with …

Purpose The combination of gemcitabine plus bevacizumab produced a 21% response rate
and a median survival of 8.8 months in a multicenter phase II trial in patients with metastatic …

Autologous dendritic cells (DCs) transfected with mRNA encoding prostate-specific antigen
(PSA) are able to stimulate potent, T cell–mediated antitumor immune responses in vitro. A …

Autologous dendritic cells transfected with total renal tumor RNA have been shown to be
potent stimulators of CTLs and antitumor immunity in vitro. A Phase I trial was conducted to …

PURPOSE: We postulated that the pathologic evaluation of the lymph nodes of surgical
specimens from patients with rectal cancer can have a substantial impact on time to relapse …

Background Since 2004, a regimen of 6 months of treatment with oxaliplatin plus a
fluoropyrimidine has been standard adjuvant therapy in patients with stage III colon cancer …

Importance Combining biologic monoclonal antibodies with chemotherapeutic cytotoxic
drugs provides clinical benefit to patients with advanced or metastatic colorectal cancer, but …

Purpose Randomized studies have shown that irinotecan (CPT-11) extends survival in
metastatic colorectal cancer patients when administered in second-line and when added to …