Classification and functions of enteroendocrine cells of the lower gastrointestinal tract

AR Gunawardene, BM Corfe… - International journal of …, 2011 - Wiley Online Library
With over thirty different hormones identified as being produced in the gastrointestinal (GI)
tract, the gut has been described as 'the largest endocrine organ in the body'(Ann. Oncol …

[HTML][HTML] Protein for life: Review of optimal protein intake, sustainable dietary sources and the effect on appetite in ageing adults

M Lonnie, E Hooker, JM Brunstrom, BM Corfe… - Nutrients, 2018 - mdpi.com
With an ageing population, dietary approaches to promote health and independence later in
life are needed. In part, this can be achieved by maintaining muscle mass and strength as …

Neuropilins: expression and roles in the epithelium

JRL Wild, CA Staton, K Chapple… - International journal of …, 2012 - Wiley Online Library
Initially found expressed in neuronal and then later in endothelial cells, it is well established
that the transmembrane glycoproteins neuropilin‐1 (NRP1) and neuropilin‐2 (NRP2) play …

Dysbiosis of the gut microbiota in disease

S Carding, K Verbeke, DT Vipond… - Microbial ecology in …, 2015 - Taylor & Francis
There is growing evidence that dysbiosis of the gut microbiota is associated with the
pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include …

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

GJ Griffiths, L Dubrez, CP Morgan, NA Jones… - The Journal of cell …, 1999 - rupress.org
Investigation of events committing cells to death revealed that a concealed NH2-terminal
epitope of the pro-apoptotic protein Bak became exposed in vivo before apoptosis. This …

Localization of GerAA and GerAC Germination Proteins in the Bacillus subtilis Spore

KD Hudson, BM Corfe, EH Kemp, IM Feavers… - Journal of …, 2001 - Am Soc Microbiol
ABSTRACT The GerAA,-AB, and-AC proteins of the Bacillus subtilis spore are required for
the germination response tol-alanine as the sole germinant. They are likely to encode the …

[HTML][HTML] Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line

JS Waby, H Chirakkal, CW Yu, GJ Griffiths… - Molecular cancer, 2010 - Springer
Butyrate, a known histone deacetylase inhibitor (HDACi) and product of fibre fermentation, is
postulated to mediate the protective effect of dietary fibre against colon cancer. The …

[HTML][HTML] Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

GWJ Makin, BM Corfe, GJ Griffiths… - The EMBO …, 2001 - embopress.org
Damage‐induced Bax N‐terminal change, translocation to mitochondria and formation of Bax
dimers/complexes occur regardless of cell fate | The EMBO Journal Skip to Article Content Skip …

[HTML][HTML] Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation

DCW Yu, JS Waby, H Chirakkal, CA Staton, BM Corfe - Molecular cancer, 2010 - Springer
Background Neuropilin is a transmembrane receptor for vascular endothelial growth factor
(VEGF) and is expressed in normal endothelial cells and upregulated in cancer cells …

[HTML][HTML] The interdependency and co-regulation of the vitamin D and cholesterol metabolism

T Warren, R McAllister, A Morgan, TS Rai, V McGilligan… - Cells, 2021 - mdpi.com
Vitamin D and cholesterol metabolism overlap significantly in the pathways that contribute to
their biosynthesis. However, our understanding of their independent and co-regulation is …