Probiotic approach to prevent antibiotic resistance

AC Ouwehand, S Forssten, AA Hibberd, A Lyra… - Annals of …, 2016 - Taylor & Francis
Probiotics are live microorganisms, mainly belonging to the genera Lactobacillus and
Bifidobacterium, although also strain of other species are commercialized, that have a …

[HTML][HTML] Microbial community analysis reveals high level phylogenetic alterations in the overall gastrointestinal microbiota of diarrhoea-predominant irritable bowel …

L Krogius-Kurikka, A Lyra, E Malinen… - BMC …, 2009 - Springer
Background A growing amount of scientific evidence suggests that microbes are involved in
the aetiology of irritable bowel syndrome (IBS), and the gastrointestinal (GI) microbiota of …

Intestinal microbiota is altered in patients with colon cancer and modified by probiotic intervention

AA Hibberd, A Lyra, AC Ouwehand… - BMJ open …, 2017 - bmjopengastro.bmj.com
Objective The colonic microbiota is altered in patients with colorectal cancer (CRC). We
investigated the microbiota composition of patients with colon cancer compared with …

[HTML][HTML] Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome

E Malinen, L Krogius-Kurikka, A Lyra… - World journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To investigate the correlations between self-reported symptoms of irritable bowel
syndrome (IBS) and the gastrointestinal (GI) microbiota composition. METHODS: Fecal …

[HTML][HTML] Diarrhoea-predominant irritable bowel syndrome distinguishable by 16S rRNA gene phylotype quantification

A Lyra, T Rinttilä, J Nikkilä… - World journal of …, 2009 - ncbi.nlm.nih.gov
AIM: To study whether selected bacterial 16S ribosomal RNA (rRNA) gene phylotypes are
capable of distinguishing irritable bowel syndrome (IBS). METHODS: The faecal microbiota …

[HTML][HTML] Irritable bowel syndrome symptom severity improves equally with probiotic and placebo

A Lyra, M Hillilä, T Huttunen, S Männikkö… - World journal of …, 2016 - ncbi.nlm.nih.gov
AIM To determine the effects of Lactobacillus acidophilus NCFM on irritable bowel syndrome
(IBS) symptoms and quality of life (QoL). METHODS In this randomized triple-blind trial, adult …

[HTML][HTML] Effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes

A Lyra, L Krogius-Kurikka, J Nikkilä, E Malinen… - BMC …, 2010 - Springer
Background Probiotics can alleviate the symptoms of irritable bowel syndrome (IBS),
possibly by stabilizing the intestinal microbiota. Our aim was to determine whether IBS …

[HTML][HTML] Nasal microbiota clusters associate with inflammatory response, viral load, and symptom severity in experimental rhinovirus challenge

MJ Lehtinen, AA Hibberd, S Männikkö, N Yeung… - Scientific reports, 2018 - nature.com
The role of nasal and fecal microbiota in viral respiratory infections has not been
established. We collected nasal swabs and washes, and fecal samples in a clinical study …

[HTML][HTML] Real-time PCR analysis of enteric pathogens from fecal samples of irritable bowel syndrome subjects

T Rinttilä, A Lyra, L Krogius-Kurikka, A Palva - Gut Pathogens, 2011 - Springer
Background Growing amount of scientific evidence suggests that microbes are involved in
the pathophysiology of irritable bowel syndrome (IBS). The predominant fecal microbiota …

[HTML][HTML] Comparison of bacterial quantities in left and right colon biopsies and faeces

A Lyra, S Forssten, P Rolny, Y Wettergren… - World journal of …, 2012 - ncbi.nlm.nih.gov
METHODS: Twenty patients undergoing diagnostic colonoscopy with endoscopically and
histologically normal mucosa were recruited to the study, 14 subjects of which also supplied …