Natural history and hepatocellular carcinoma risk in untreated chronic hepatitis B patients with indeterminate phase

DQ Huang, X Li, MH Le, AK Le, YH Yeo… - Clinical …, 2022 - Elsevier
Background & Aims Many patients with chronic hepatitis B (CHB) may not conform to any of
the defined phases and hence are classified as indeterminate. We aimed to characterize the …

Association between fatty liver and cirrhosis, hepatocellular carcinoma, and hepatitis B surface antigen seroclearance in chronic hepatitis B

J Li, HI Yang, ML Yeh, MH Le, AK Le… - The Journal of …, 2021 - academic.oup.com
Abstract Background Chronic hepatitis B (CHB) and fatty liver (FL) are common, natural
history data on concurrent FL and CHB (FL-CHB) are limited. This study aimed to evaluate …

HCV genotype 6 increased the risk for hepatocellular carcinoma among Asian patients with liver cirrhosis

MH Lee, TI Hsiao, SR Subramaniam… - Official journal of the …, 2017 - journals.lww.com
Objectives: Hepatitis C virus (HCV) infection is a well-documented risk factor for
hepatocellular carcinoma (HCC). Seven HCV genotypes have been classified, and the …

Changes in renal function in patients with chronic HBV infection treated with tenofovir disoproxil fumarate vs entecavir

S Trinh, AK Le, ET Chang, J Hoang, D Jeong… - Clinical …, 2019 - Elsevier
Background & Aims It is unclear whether drugs used to treat chronic hepatitis B virus (HBV)
infection cause significant renal impairment. We compare adjusted mean estimated …

Poor adherence to guidelines for treatment of chronic hepatitis B virus infection at primary care and referral practices

VH Nguyen, AK Le, HN Trinh, M Chung… - Clinical …, 2019 - Elsevier
Background & Aims The American Association for the Study of Liver Diseases (AASLD)
guidelines for treatment of chronic hepatitis B virus (HBV) infection have changed with time …

Fatty liver is not independently associated with the rates of complete response to oral antiviral therapy in chronic hepatitis B patients

J Li, AK Le, KT Chaung, L Henry, JK Hoang… - Liver …, 2020 - Wiley Online Library
Background & aims Nonalcoholic fatty liver disease (NAFLD) and chronic hepatitis B (CHB)
are common liver diseases. Concurrent NAFLD may affect antiviral treatment outcomes in …

[PDF][PDF] Effects of cirrhosis and diagnosis scenario in metabolic‐associated fatty liver disease‐related hepatocellular carcinoma

VL Chen, ML Yeh, JD Yang, J Leong… - Hepatology …, 2021 - Wiley Online Library
Metabolic‐associated fatty liver disease (MAFLD) is a major cause of liver‐related
complications, including hepatocellular carcinoma (HCC). While MAFLD‐related HCC is …

[HTML][HTML] Validity of international classification of diseases, tenth revision, codes for cirrhosis

NS Ramrakhiani, MH Le, YH Yeo, AK Le, M Maeda… - Digestive …, 2021 - karger.com
Introduction: Accurate identification of patients with cirrhosis is important for research using
administrative databases. We aimed to examine the accuracy of several major ICD-10 codes …

Autoantibodies in chronic hepatitis C virus infection: impact on clinical outcomes and extrahepatic manifestations

AJ Gilman, AK Le, C Zhao, J Hoang… - BMJ Open …, 2018 - bmjopengastro.bmj.com
Goals To examine the role that autoantibodies (auto-abs) play in chronic hepatitis C virus
(HCV) regarding demographics, presence of extrahepatic manifestations and long-term …

Early multiplexed detection of cirrhosis using giant magnetoresistive biosensors with protein biomarkers

E Ng, AK Le, MH Nguyen, SX Wang - ACS sensors, 2020 - ACS Publications
Liver cirrhosis is one of the leading causes of death in adults worldwide. It is highly prevalent
in developing countries and is growing in prevalence in developed countries mostly …