Short term clinical outcome of children with rotavirus infection at Kenyatta National Hospital, Nairobi

East Afr Med J. 2010 Jun;87(6):242-7. doi: 10.4314/eamj.v87i6.63082.

Abstract

Background: Rotavirus infection is the single most common cause of acute gastroenteritis in children under five years of age. Rotavirus gastroenteritis has a high morbidity and mortality in children in Kenya.

Objectives: To determine the short term clinical outcome for children admitted to Kenyatta National Hospital with rotavirus gastroenteritis and the correlates of poor outcome.

Design: Short longitudinal survey.

Setting: Kenyatta National Hospital from February to May 2008.

Subjects: Five hundred children were screened using a rapid antigen detection kit and ELISA.

Results: Of the 191 children who tested positive for rotavirus in stool; 172 children were recruited into the study. Eighty eight per cent of the patients were discharged within one week, 8.1% stayed for more than seven days while 4.1% died. Children who had co-morbidities such as malnutrition, rickets and pneumonia had worse outcomes.

Conclusion: Rotavirus gastroenteritis has a long hospital stay and a high mortality. Children in shock on admission and those with co-morbid conditions should get priority for they have a poor outcome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Hospitalization
  • Humans
  • Kenya
  • Longitudinal Studies
  • Male
  • Rotavirus Infections / complications
  • Rotavirus Infections / diagnosis*
  • Rotavirus Infections / therapy*
  • Time Factors
  • Treatment Outcome