Endoscopic ultrasound-guided biliary drainage with placement of a fully covered metal stent for malignant biliary obstruction

World J Gastroenterol. 2012 May 28;18(20):2526-32. doi: 10.3748/wjg.v18.i20.2526.

Abstract

Aim: To determine the utility of endoscopic ultrasound-guided biliary drainage (EUS-BD) with a fully covered self-expandable metal stent for managing malignant biliary stricture.

Methods: We collected data from 13 patients who presented with malignant biliary obstruction and underwent EUS-BD with a nitinol fully covered self-expandable metal stent when endoscopic retrograde cholangiopancreatography (ERCP) fails. EUS-guided choledochoduodenostomy (EUS-CD) and EUS-guided hepaticogastrostomy (EUS-HG) was performed in 9 patients and 4 patients, respectively.

Results: The technical and functional success rate was 92.3% (12/13) and 91.7% (11/12), respectively. Using an intrahepatic approach (EUS-HG, n = 4), there was mild peritonitis (n = 1) and migration of the metal stent to the stomach (n = 1). With an extrahepatic approach (EUS-CD, n = 10), there was pneumoperitoneum (n = 2), migration (n = 2), and mild peritonitis (n = 1). All patients were managed conservatively with antibiotics. During follow-up (range, 1-12 mo), there was re-intervention (4/13 cases, 30.7%) necessitated by stent migration (n = 2) and stent occlusion (n = 2).

Conclusion: EUS-BD with a nitinol fully covered self-expandable metal stent may be a feasible and effective treatment option in patients with malignant biliary obstruction when ERCP fails.

Keywords: Biliary drainage; Biliary obstruction; Endoscopic ultrasound-guided; Metal stent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged, 80 and over
  • Anastomosis, Surgical
  • Bile Duct Neoplasms / complications
  • Bile Ducts, Intrahepatic
  • Cholangiocarcinoma / complications
  • Choledochostomy
  • Cholestasis / etiology
  • Cholestasis / surgery*
  • Common Bile Duct Neoplasms / complications*
  • Drainage / methods*
  • Endosonography
  • Female
  • Hepatic Duct, Common / surgery
  • Humans
  • Klatskin Tumor / complications
  • Male
  • Middle Aged
  • Palliative Care*
  • Pancreatic Neoplasms / complications*
  • Stents
  • Stomach / surgery
  • Ultrasonography, Interventional*