Predictors of recurrent esophageal food impaction: a case-control study

J Clin Gastroenterol. 2008 Aug;42(7):771-5. doi: 10.1097/MCG.0b013e31815576d2.

Abstract

Background: Esophageal food impaction (FI) is a distressing condition requiring urgent endoscopic intervention, with a reported recurrence rate between 10% and 20%. Knowledge of factors predisposing to recurrent FI may enable preventive measures to minimize the risk of recurrence.

Objective: To identify risk factors associated with recurrent FI.

Design: Retrospective case-control study.

Setting: Tertiary referral center.

Patients: A prospectively maintained database and medical records of all patients undergoing emergent endoscopy for FI from 1989 to 2000 were reviewed. Cases were defined as those presenting with more than 1 episode of FI, whereas controls were defined as those without recurrence within 5 years of the index episode. Several demographic, clinical, endoscopic, and follow-up variables were extracted. Statistical analysis included chi2 tests and t tests for univariate analysis, and stepwise logistic regression for multivariate analysis.

Interventions: NA.

Main outcome measurements: Predictors of recurrent FI.

Results: A total of 52 cases and 124 controls were identified (recurrence rate 30%). Presence of a diaphragmatic hernia [odds ratio (OR) 2.65; confidence interval (CI) 1.19-5.89], disimpaction by piecemeal extraction (OR 2.32; CI 1.09-4.97), and acquisition of esophageal biopsies (OR 3.69; CI 1.42-9.66) increased odds for recurrent FI. Physician follow-up after FI decreased the odds for recurrent FI (OR 0.38; CI 0.18-0.80).

Limitations: Retrospective study.

Conclusions: The presence of a diaphragmatic hernia, complexity of endoscopic disimpaction technique, and lack of follow-up increased risk for recurrent FI. Collection of esophageal biopsies as a risk factor suggests a visibly more severe esophageal disorder as a potential cause for recurrent FI.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Esophageal Stenosis / complications
  • Esophagitis / complications
  • Esophagoscopy / adverse effects
  • Esophagus*
  • Female
  • Food*
  • Foreign Bodies*
  • Hernia, Hiatal / complications
  • Humans
  • Male
  • Meat
  • Middle Aged
  • Recurrence
  • Risk Factors