Original ResearchFull Report: Clinical—LiverSimeprevir With Peginterferon and Ribavirin Leads to High Rates of SVR in Patients With HCV Genotype 1 Who Relapsed After Previous Therapy: A Phase 3 Trial
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Conflicts of interest These authors disclose the following: Xavier Forns has received unrestricted grant support from Jansen and Merck Sharp and Dohme Ltd (MSD), and has acted as an advisor for Jansen, Gilead, MSD, and Abbott. Eric Lawitz has received research/grant support from AbbVie, Achillion Pharmaceuticals, Boehringer Ingelheim, Bristol-Myers Squibb (BMS), Gilead Sciences, GlaxoSmithKline, Idenix Pharmaceuticals, Intercept Pharmaceuticals, Janssen, Medtronic, Merck & Co, Novartis, Presidio, Roche, Santaris Pharmaceuticals, and Vertex Pharmaceuticals; has acted as a speaker for Gilead, Kadmon, Merck, and Vertex; and has participated in Advisory Boards for AbbVie, Achillion Pharmaceuticals, BioCryst, Biotica, Enanta, Idenix Pharmaceuticals, Janssen, Merck & Co, Novartis, Santaris Pharmaceuticals, Theravance, and Vertex Pharmaceuticals. Stefan Zeuzem has acted as a consultant for Abbvie, Achillion, BMS, Boehringer Ingelheim, Gilead, Idenix, Janssen, Merck, Novartis, Presidio, Roche, Santaris, and Vertex. Ed Gane has acted as an advisor for Janssen, Gilead, AbbVie, Novartis, Tibotec, Achillion, and Roche; and as a speaker for Gilead, Roche, and Novartis. Jean Pierre Bronowicki has been a clinical investigator, speaker, and/or consultant for Boehringer Ingelheim, BMS, Gilead Sciences, Janssen Pharmaceuticals, MSD, Novartis, and Roche. Pietro Andreone has received research grants from Gilead, MSD, and Roche, and has acted as an advisor for Janssen, MSD, and Roche; and as a consultant for BMS and MSD. Ashley Brown has acted as an advisor and/or speaker for Abbvie, Achillion, BMS, Boehringer Ingelheim, Gilead, Janssen, Merck, Novartis, Presidio, and Roche. Monika Peeters, Oliver Lenz, Rekha Sinha, and Maria Beumont–Mauviel are employees of Janssen Infectious Diseases. Sivi Ouwerkerk–Mahadevan is an employee of Janssen Research & Development. Jane Scott, Guy De La Rosa, and Ronald Kalmeijer are employees of Janssen Global Services, LLC. Andrzej Horban discloses no conflicts.
Funding Supported by Janssen.