ReportThe specific dermatoses of pregnancy revisited and reclassified: Results of a retrospective two-center study on 505 pregnant patients
Section snippets
Methods
During a 10-year period, a total of 596 consecutive pregnant patients were seen for various skin diseases in a center in London, United Kingdom (1994-2004, n = 420), and another in Graz, Austria (1999-2004, n = 176). A retrospective review was performed by means of medical record analysis. Data from 505 patients (London, n = 355; Graz, n = 150) who presented with a generalized pruritic skin condition that first developed during their pregnancy were included into this study. Excluded were 95
Results
A total of 505 patients with a median age of 30 years (range: 15-45 years) were included into this study. In all, 104 patients (20.6%) given a diagnosis of miscellaneous skin diseases coinciding with pregnancy were not further analyzed and are detailed in Table II. The other 401 patients were categorized as follows: EP, 251 patients (49.7%); PEP, 109 (21.6%); PG, 21 (4.2%); ICP, 15 (3.0%); PP, 4 (0.8%); and PF, 1 (0.2%).
The most frequent skin disorder in pregnancy seen in our patients was EP.
Discussion
There are limited data on the frequency and clinical characteristics of the various pruritic dermatoses of pregnancy and their terminology has been misleading and confusing. The two current classification schemes are equivocal and include entities of provisional character. The recent observation of a high prevalence of EP, making it a crucial differential diagnostic consideration, is not acknowledged by either of them. In this retrospective two-center study on 505 pregnant patients with a
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