Original articleClinical endoscopyEUS elastography for diagnosis of solid pancreatic masses: a meta-analysis
Section snippets
Study selection
We defined inclusion and exclusion criteria by discussion before the literature search. Studies that met the following inclusion criteria were selected: (1) the use of EUS elastography for diagnosis of solid pancreatic masses; (2) solid pancreatic mass was the only lesion or combining with other lesions but analyzed separately; (3) the use of a reference standard of EUS-FNA cytology, surgical histology or clinical follow-up of at least 6 months; (4) written in English; (5) providing enough data
Results
The original search with predefined search strategy yielded 124 studies, and we retrieved 13 articles eligible for final analysis. The detailed flow chart was shown in Figure 1. The characteristics of the included studies are shown in Table 1. There were 9 studies published as full texts and 4 studies published as abstracts. A total of 1044 patients were investigated in the analysis. Of the 13 articles, 6 studies used color pattern as a diagnostic standard,18, 20, 23, 24, 26, 27 3 studies used
Discussion
EUS that provides high-quality sonographic images has been considered as one of the most reliable and accurate techniques for the diagnosis and staging of pancreatic cancer since its development in the 1980s.34, 35 Regardless of the development in imaging quality and resolution, the differential diagnosis of solid pancreatic masses remains a challenge in clinical work.6 In this context, EUS-FNA that obtains cytologic samples is considered as a useful and accurate tool for diagnosis of solid
References (47)
- et al.
EUS, PET, and CT scanning for evaluation of pancreatic adenocarcinoma
Gastrointest Endosc
(2000) - et al.
Endoscopic ultrasound-guided biopsy for the evaluation of pancreatic tumors
Gastroenterol Hepatol
(2007) - et al.
Utility of a repeated EUS at a tertiary-referral center
Gastrointest Endosc
(2008) - et al.
Yield of EUS-guided FNA of pancreatic masses in the presence or the absence of chronic pancreatitis
Gastrointest Endosc
(2005) - et al.
Frequency of major complications after EUS-guided FNA of solid pancreatic masses: a prospective evaluation
Gastrointest Endosc
(2006) - et al.
Endoscopic ultrasound-guided, 18-gauge, fine needle aspiration biopsy of the pancreas using a 2.8 mm channel convex array echoendoscope
Gastrointest Endosc
(1998) - et al.
Elastography in the detection of prostatic cancer
Clin Radiol
(2002) - et al.
Real-time sonoelastography of the cervix: tissue elasticity of the normal and abnormal cervix
Acad Radiol
(2007) - et al.
EUS elastography for the differentiation of benign and malignant lymph nodes: a meta-analysis
Gastrointest Endosc
(2011) - et al.
Dynamic analysis of EUS used for the differentiation of benign and malignant lymph nodes
Gastrointest Endosc
(2007)
Combined contrast-enhanced power Doppler and real-time sonoelastography performed during EUS, used in the differential diagnosis of focal pancreatic masses (with videos)
Gastrointest Endosc
Quantitative endoscopic ultrasound elastography: an accurate method for the differentiation of solid pancreatic masses
Gastroenterology
EUS elastography for the characterization of solid pancreatic masses
Gastrointest Endosc
Neural network analysis of dynamic sequences of EUS elastography used for the differential diagnosis of chronic pancreatitis and pancreatic cancer
Gastrointest Endosc
Contrast EUS versus EUS sono-elastography in the differentiation of atypical pancreatic masses [abstract]
Gastrointest Endosc
Evaluation of pancreatic tumors with contrast enhanced-endoscopic ultrasonography and EUS-strain ratio elastography [abstract]
Gastrointest Endosc
The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed
J Clin Epidemiol
EUS, PET, and CT scanning for evaluation of pancreatic adenocarcinoma
Gastrointest Endosc
Endosonography-guided fine needle aspiration biopsy in the evaluation of pancreatic masses
Am J Gastroenterol
The clinical utility of endoscopic ultrasound-guided fine-needle aspiration in the diagnosis and staging of pancreatic carcinoma
Gastrointest Endosc
EUS-guided FNA of solid pancreatic masses: a learning curve with 300 consecutive procedures
Gastrointest Endosc
EUS elastography of the pancreas: feasibility and pattern description of the normal pancreas, chronic pancreatitis, and focal pancreatic lesions
Gastrointest Endosc
Gastrointestinal imaging: endoscopic ultrasound
Gastroenterology
Cited by (119)
Differentiation of bladder cancer with water flow elastography (WaFE)
2024, Journal of the Mechanical Behavior of Biomedical MaterialsWater flow elastography – A promising tool to measure tissue stiffness during minimally invasive surgery
2023, Journal of the Mechanical Behavior of Biomedical MaterialsEndoscopic Ultrasound (EUS) Guided Elastography
2023, Diagnostics
DISCLOSURE: All authors disclosed no financial relationships relevant to this publication.