Demographics and baseline disease characteristics
| Characteristic | All patients (n=205) |
| Sex, n (%) | |
| Female | 82 (40.0) |
| Male | 123 (60.0) |
| Median (range) age, years | 35.0 (18.0–79.0) |
| Race, n (%) | |
| White | 166 (81.0) |
| Asian | 28 (13.7) |
| Multiracial* | 6 (2.9) |
| Black or African American | 5 (2.4) |
| Median (range) disease duration, y ears | 3.9 (0.3–38.8) |
| Disease extent | |
| Left-sided colitis | 97 (47.3) |
| Pancolitis (extensive) | 64 (31.2) |
| Unknown | 44 (21.5) |
| Mean (SD) partial Mayo score | 6.4 (1.40) |
| Mean (SD) full Mayo score (n=92) | 8.7 (1.65) |
| Stool frequency score (SFS), n (%) | |
| SFS 0 (Normal) | 3 (1.5) |
| SFS 1 (1–2 stools more than normal) | 16 (7.8) |
| SFS 2 (3–4 stools more than normal) | 64 (31.2) |
| SFS 3 (≥5 stools more than normal) | 122 (59.5) |
| Rectal bleeding score (RBS), n (%) | |
| RBS 0 (No blood seen)† | 6 (2.9) |
| RBS 1 (Streaks of blood with stool less than half of the time) | 77 (37.6) |
| RBS 2 (Obvious blood with stool most of the time) | 94 (45.9) |
| RBS 3 (Blood alone passed) | 28 (13.7) |
| Endoscopic findings (n=92), n (%) | |
| Mild disease‡ | 5 (5.4) |
| Moderate disease§ | 58 (63.0) |
| Severe disease¶ | 29 (31.5) |
| Physician global assessment (PGA), n (%) | |
| PGA 0 (Normal) | 1 (0.5) |
| PGA 1 (Mild disease) | 1 (0.5) |
| PGA 2 (Moderate disease) | 150 (73.2) |
| PGA 3 (Severe disease) | 53 (25.9) |
| Concomitant medications, n (%) | |
| 5-Aminosalicylates | 145 (70.7) |
| Azathioprine | 93 (45.4) |
| Corticosteroids | 80 (39.0) |
| 6-Mercaptopurine | 19 (9.3) |
| Methotrexate | 6 (2.9) |
*Defined as have ≥2 of American Indian or Alaska native, black or African-American, Native Hawaiian or other Pacific islander, White or Asian.
†The six patients with rectal bleeding subscore 0 were included in the analysis; no patient selection was performed for the analysis.
‡Mild disease = erythema , decreased vascular pattern, mild friability.
§Moderate disease = marked erythema , absent vascular pattern, friability, erosions.
¶Severe disease = spontaneous bleeding , ulceration.