Table 2

Independent predictors of overall mortality in NHANES III

PredictorsaHR95% CIP value
NFS as a continuous predictor
 NFS1.0620.997 to 1.1310.0599
 Age, years1.0761.067 to 1.084<0.0001
 Male1.4241.228 to 1.65<0.0001
 Black1.2361.035 to 1.4760.0193
 Hypertension1.3981.196 to 1.635<0.0001
 Diabetes1.7091.44 to 2.028<0.0001
 CHF1.7811.391 to 2.279<0.0001
 Stroke1.8451.374 to 2.478<0.0001
 Smoking1.7481.471 to 2.076<0.0001
Conventional NFS thresholds for high and low
 High NFS1.3721.073 to 1.7550.0118
 Low NFS0.9170.768 to 1.0960.3407
 Age, years1.0771.069 to 1.085<0.0001
 Male1.4411.242 to 1.672<0.0001
 Black1.2421.042 to 1.4810.0156
 Hypertension1.4041.201 to 1.642<0.0001
 Diabetes1.6941.433 to 2.003<0.0001
 CHF1.7681.382 to 2.261<0.0001
 Stroke1.8451.376 to 2.475<0.0001
 Smoking1.7411.467 to 2.067<0.0001
Best NFS threshold of 0.8
 NFS (0.8)1.4111.085 to 1.8340.0102
 Age, years1.0781.071 to 1.086<0.0001
 Male1.4381.241 to 1.667<0.0001
 Black1.2511.05 to 1.490.0121
 Hypertension1.4061.202 to 1.644<0.0001
 Diabetes1.7451.487 to 2.047<0.0001
 CHF1.7831.394 to 2.282<0.0001
 Stroke1.8721.396 to 2.509<0.0001
 Smoking1.7381.465 to 2.064<0.0001
  • Adjusted HRs  were calculated using Cox proportional hazard model.

  • CHF, congestive heart failure; NAFLD, non-alcoholic fatty liver disease; NFS, NAFLD Fibrosis Score; NHANES III, National Health and Nutrition Examination Survey.