Dose and dosing schedule
| Group A | ||||||
| Dose | Day 1 | Day 8 | Day 15 | Day 22 | Day 29/day 1 of the following cycle | |
| GEM | 1000 mg/m2 | ○ | ○ | ○ | Withdrawal | ○ |
| Group B | ||||||
| Dose | Day 1 | Day 8 | Day 15 | Day 22/day 1 of the following cycle | ||
| GEM | 1000 mg/m2 | ○ | ○ | Withdrawal | ○ | |
| S-1 | 65 mg/m2/day | <--days 1–14--> | ||||
GEM, gemcitabine hydrochloride.