Table 2

Schedule of events—SMPC arm

SMPC arm visit#	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Week	−4	0	2	6	10	14	18	22	26	30	34	38	42	46
Prestudy medical screening	x
Consent by consultant	x
Clinical lab (haematology)	x					x								x
Clinical lab (biochemistry)	x					x								x
Clinical lab (HCG)	x
Clinical lab (stool C&S)	x
	x
Blood drawn for GLM drug levels and ADA	x					x								x
FCP stool sample		*x				x								x
Mayo score	x													x
Partial Mayo score						x
Colonoscopy/sigmoidoscopy†	x													x
Short Health Scale		x	x	x	x	x	x	x	x	x	x	x	x	x
Modified partial Mayo		x	x	x	x	x	x	x	x	x	x	x	x	x
GLM drug administration by research nurse		x	x

*Initial FCP may done at screening or baseline visit.
†Colonoscopy/sigmoidoscopy (w/Mayo score) to be completed within 12 weeks (±4 weeks) of baseline visit. Window for week 46 colonoscopy/sigmoidoscopy is also ±4 weeks.
ADA, adalimumab; FCP, faecal calprotectin; GLM, golimumab.