Men | Women | All | |||||||
Siblings | O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI |
One sibling | 14 416 | 1.56 | 1.54 to 1.59 | 31 683 | 1.54 | 1.52 to 1.56 | 46 099 | 1.55 | 1.53 to 1.56 |
<30 | 1043 | 2.17 | 2.04 to 2.31 | 6558 | 2.04 | 1.99 to 2.09 | 7601 | 2.06 | 2.01 to 2.10 |
40–49 | 5955 | 1.75 | 1.70 to 1.79 | 13 996 | 1.56 | 1.53 to 1.58 | 19 951 | 1.61 | 1.59 to 1.63 |
50+ | 7418 | 1.39 | 1.36 to 1.42 | 11 129 | 1.32 | 1.30 to 1.35 | 18 547 | 1.35 | 1.33 to 1.37 |
Two siblings | 2233 | 12.76 | 12.23 to 13.30 | 4651 | 9.25 | 8.99 to 9.52 | 6884 | 10.16 | 9.92 to 10.40 |
<30 | 155 | 20.39 | 17.31 to 23.87 | 1018 | 11.06 | 10.39 to 11.76 | 1173 | 11.77 | 11.11 to 12.47 |
40–49 | 909 | 13.70 | 12.83 to 14.62 | 1977 | 8.65 | 8.27 to 9.04 | 2886 | 9.79 | 9.43 to 10.15 |
50+ | 1169 | 11.56 | 10.91 to 12.25 | 1656 | 9.10 | 8.67 to 9.55 | 2825 | 9.98 | 9.62 to 10.36 |
Three siblings | 415 | 11.84 | 10.72 to 13.03 | 898 | 9.58 | 8.96 to 10.22 | 1313 | 10.19 | 9.65 to 10.76 |
<30 | 37 | 25.78 | 18.14 to 35.56 | 217 | 13.17 | 11.47 to 15.04 | 254 | 14.18 | 12.49 to 16.03 |
40–49 | 158 | 12.31 | 10.46 to 14.39 | 375 | 8.66 | 7.81 to 9.59 | 533 | 9.50 | 8.71 to 10.34 |
50+ | 220 | 10.58 | 9.23 to 12.08 | 306 | 9.00 | 8.02 to 10.06 | 526 | 9.60 | 8.79 to 10.45 |
Four or more siblings | 115 | 14.78 | 12.20 to 17.74 | 215 | 9.46 | 8.24 to 10.81 | 330 | 10.81 | 9.68 to 12.05 |
<30 | 15 | 39.80 | 22.21 to 65.80 | 66 | 15.06 | 11.65 to 19.17 | 81 | 17.02 | 13.52 to 21.16 |
40–49 | 49 | 16.56 | 12.25 to 21.91 | 80 | 7.85 | 6.23 to 9.78 | 129 | 9.81 | 8.19 to 11.66 |
50+ | 51 | 11.47 | 8.54 to 15.09 | 69 | 8.45 | 6.57 to 10.70 | 120 | 9.52 | 7.89 to 11.38 |
O, observed number of cases; SIR, standardised incidence ratio.