Demographics and background information
| Patient overview | Overall | ||
|---|---|---|---|
| Demographics (n=1036) | |||
| Age: range: 6–89 mean (SD) | 49.7 (17) | ||
| Gender: male | 364 (35%) | ||
| Ethnicity | |||
| White | 801 (77%) | ||
| Mixed | 6 (0.6%) | ||
| Asian or Asian British | 36 (34%) | ||
| Black or Black British | 11 (1.1%) | ||
| Chinese or other ethnic group | 10 (1.0%) | ||
| Not stated | 172 (17%) | ||
| Suspected BAM type (n=752) | |||
| BAM type 1 | 107 (14%) | ||
| Crohn's disease (yes) | 85 | ||
| Ileal damage (yes) | 46 | ||
| Radiotherapy suspected of causing BAM type 1 | 1 | ||
| BAM type 2 | 335 (45%) | ||
| BAM type 3 | 310 (41%) | ||
| IBS diagnosed (yes) | 78 | ||
| IBS suspected | 93 | ||
| Predominant IBS subtype among IBS diagnosed/suspected patients (n=171) | |||
| Constipation (IBS-C) | 2 | ||
| Diarrhoea (IBS-D) | 141 | ||
| Alternating (IBS-A) | 22 | ||
| Postcholecystectomy | 98 | ||
| Diabetes | 35 | ||
| Coeliac disease | 14 | ||
| Microscopic colitis | 13 | ||
| Collagenous colitis | 5 | ||
| Lymphocytic colitis | 5 | ||
| Patient is taking medications that may influence the SeHCAT test (n=732) | |||
| Yes | 117 (16%) | ||
| Type of medication | |||
| Bile acid sequestrants | 9 | ||
| Powerful anti-inflammatory drugs | 21 | ||
| Drugs affecting bowel motility (eg, opiates) | 78 | ||
| Other* | 12 | ||
| Lengths of time patients have had diarrhoea (or related symptoms) (n=736) | |||
| Less than 12 months | 180 (24%) | ||
| 1–3 years | 235 (32%) | ||
| 3–5 years | 106 (14%) | ||
| Longer than 5 years | 181 (25%) | ||
| Not known | 34 (5%) | ||
| Diagnostic tests that have been performed since beginning of symptoms | |||
| Suspected BAM type | BAM type 1 (n=107) | BAM type 2 (n=335) | BAM type 3 (n=310) |
| Blood tests | 98 | 305 | 274 |
| Stool tests | 80 | 218 | 185 |
| Colonoscopy | 90 | 255 | 234 |
| Flexible sigmoidoscopy | 12 | 43 | 41 |
| Oesphagogastroduodenoscopy | 14 | 68 | 104 |
| Complex imaging (eg, CT, MRI) | 53 | 86 | 73 |
| Other | 3 | 11 | 16 |
*Other types of medication listed include the following: codeine, loperamide, immodium, l-thyroxine, infliximab, ammitryptiline, aspirin, ibuprofen, colesevalam, metronidazole.
BAM, bile acid malabsorption; IBS, irritable bowel syndrome; SeHCAT, tauroselcholic (75selenium) acid.