Manometric data and ambulatory 24 hour pH scores in the two groups
| Normal (n=71) | IEM (n=43) | |
|---|---|---|
| HRIM | ||
| LESP (mean±SEM in mm Hg) | 22.8±1.5 | 19.8±1.6 |
| DCI (mean±SEM in mm Hg*s*cm) | 1649.5±162 | 287.8±22* |
| Fragmented peristalsis (%±SEM) | 16.2±2.6 | 47.2±3.9* |
| Ambulatory pH | ||
| pH time pH<4.0 (mean %±SEM) | 16.0±1.9 | 16.4±1.8 |
| Number of long reflux episodes (mean±SEM) | 7.7±0.8 | 8.8±0.9 |
| Duration of long reflux episodes (mean±SEM) | 35.0±5.3 | 47.3±6.6 |
| Per cent supine pH<4.0 (mean±SEM) | 16.1±2.7 | 18.3±3.0 |
*p<0.0001.
DCI, distal contractile integral; HRIM, high-resolution impedance manometry; IEM, ineffective oesophageal motility; LESP, lower esophageal sphincter pressure.