Demographics | |
Total patients | 344 |
Age (years)* | 46±8.7 |
Male | 75% |
Race (African American) | 84% |
Laboratory | |
CD4 (cells/mm3) | 505±320 |
Genotype 1 | 91% |
AST (U/L)† | 61 (range 43–99) |
ALT (U/L)† | 64 (range 43–101) |
Alkaline phosphatase (U/L)† | 108 (range 82–139) |
Bilirubin (mg/dL)† | 0.6 (IQR 0.4–1) |
Hyperbilirubinaemia (>1.2 mg/dL) | 15.4% |
Albumin (g/dL)* | 3.9±0.6 |
Haemoglobin (g/dL)* | 13.9±2.4 |
Platelets (109/L)* | 210±78 |
APRI† | 0.6 (range 0.1–10) |
FIB-4† | 1.81 (range 0.33–42) |
Biopsy data | |
Inflammation score* | 6.44±2.8 |
Fibrosis score* | 1.48±1.34 |
Steatosis >5% | 19% |
Steatohepatitis | 9% |
NASH | 4% |
Advanced fibrosis (Knodell score 3–4) | 31% |
*Mean±SD.
†Median (range).
ALT, alanine transaminase; AST, aspartate transaminase; NASH, non-alcoholic steatohepatitis.