Summary of biomarker studies and biomarker patients subclassified by biomarker category
| Type of marker | Number of biomarker studies | Number of biomarker patients |
| Blood markers | Total n=113 | Total n=87 220 |
| Bacterial infection/translocation | 2 | 354 |
| Albumin | 16 | 14 509 |
| ALBI score (albumin, bilirubin) | 2 | 502 |
| ALBI-FIB4 score (albumin, bilirubin, age, AST, ALT) | 3 | 5008 |
| CHESS-ALARM score (age, platelets, gender, LSM) | 1 | 633 |
| ABIDE model (AST/ALT, bilirubin, INR, T2DM, EV) | 1 | 543 |
| EPOD score (albumin, platelets, bilirubin) | 1 | 6049 |
| Fibrosis markers (ELF score (TIMP-1, PIIINP and hyaluronic acid), serum hyaluronan, collagen IV, laminin) | 4 | 1629 |
| Haematological markers (Von Willebrand factor, haematological indices, prekallikrein) | 3 | 448 |
| Renin, proBNP and copeptin | 1 | 307 |
| Serum ferritin | 1 | 101 |
| Serum miR-181b-5p | 1 | 105 |
| Platelets | 17 | 15 003 |
| AST/ALT | 7 | 1663 |
| INR | 9 | 7344 |
| Creatinine | 2 | 5291 |
| ALP | 1 | 91 |
| Gamma GT | 1 | 688 |
| Bilirubin | 8 | 12 801 |
| Golgi protein-73 | 1 | 632 |
| Insulin-like growth factor 1 | 1 | 148 |
| Prognostic liver secretome signature (PLSec: (VCAM-1, IGFBP-7, gp130, matrilysin, IL-6, CCL-21, angiogenin and protein S)) | 1 | 122 |
| CP score | 11 | 6683 |
| MELD score | 17 | 6819 |
| APRI score | 1 | 101 |
| HVPG | Total n=7 | Total n=1440 |
| HVPG | 7 | 1440 |
| Liver stiffness | Total n=14 | Total n=4319 |
| Liver stiffness | 14 | 4319 |
| Physiological | Total n=5 | Total n=984 |
| BMI | 1 | 161 |
| Mean arterial pressure | 1 | 402 |
| 6-minute walk test | 1 | 55 |
| Liver frailty index | 2 | 366 |
| Imaging | Total n=11 | Total n=3129 |
| Vascular | ||
| Thallium shunt index | 1 | 209 |
| Portal haemodynamics on Doppler ultrasonography | 1 | 110 |
| Hepquant-shunt test | 1 | 35 |
| Spleen volume-based non-invasive tool | 2 | 816 |
| Non-vascular | ||
| Liver surface nodularity measurement via CT | 2 | 517 |
| Liver-to-spleen volume ratio via CT | 1 | 1027 |
| 201Tl heart-liver radioactivity uptake ratio | 1 | 107 |
| Subcutaneous fat density (via Analytic Morphomics CT) | 1 | 111 |
| T2-mapping in gadoxetic acid-enhanced MRI | 1 | 197 |
| Miscellaneous | Total n=5 | Total n=998 |
| Collagen proportionate area | 2 | 219 |
| Diabetes | 1 | 457 |
| Thick fibrous septa on liver biopsy specimens | 1 | 168 |
| Indocyanine green retention test | 1 | 154 |
| Total | 155 biomarker studies | 98 090 biomarker patients |
ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate aminotransferase; BMI, body mass index; CP, Child-Turcotte-Pugh; HVPG, hepatic venous pressure gradient; INR, international normalised ratio; MELD, Model for End-Stage Liver Disease.