Table 2

Association between H. pylori and subsequent gastrointestinal and respiratory cancer diagnosis in patients followed in general practices in Germany (univariable Cox regression models)

Outcome diagnosisHR for H. pylori versus no H. pylori HR for H. pylori with eradication versus no H. pylori HR for H. pylori without eradication versus no H. pylori
HR (95% CI)P valueHR (95% CI)P valueHR (95% CI)P value
Cancer total 1.11 (1.04 to 1.18) 0.002 1.06 (0.97 to 1.15)0.232 1.18 (1.07 to 1.30) <0.001
Oesophagus0.49 (0.26 to 0.89)0.0200.52 (0.22 to 1.23)0.1370.45 (0.19 to 1.07)0.072
Stomach1.59 (1.00 to 2.53)0.0491.48 (0.78 to 2.83)0.2241.70 (0.87 to 3.32)0.118
Colon and rectum0.99 (0.78 to 1.26)0.9410.98 (0.72 to 1.32)0.8771.02 (0.68 to 1.54)0.910
Liver0.75 (0.41 to 1.36)0.3390.69 (0.30 to 1.58)0.3800.82 (0.35 to 1.93)0.649
Pancreas1.46 (0.99 to 2.17)0.0581.77 (1.01 to 3.12)0.0481.21 (0.70 to 2.09)0.498
Larynx1.06 (0.51 to 2.20)0.8850.87 (0.28 to 2.70)0.8041.21 (0.46 to 3.18)0.704
Bronchus and lung0.88 (0.69 to 1.11)0.278 0.60 (0.44 to 0.83) 0.002 1.51 (1.03 to 2.20)0.035