Symptom | Control group (n=42) | P value | Case group (n=44) | P value | ||||||||
Admission | 1 week | 2 weeks | 3 weeks | 4 weeks | Admission | 1 week | 2 weeks | 3 weeks | 4 weeks | |||
Rectal bleeding | 21 | 19 | 18 | 15 | 12 | 0.000* | 26 | 19 | 15 | 13 | 8 | 0.001* |
Incomplete defecation | 31 | 27 | 25 | 21 | 21 | 0.000* | 26 | 24 | 15 | 11 | 12 | 0.000* |
Anal pain | 30 | 28 | 21 | 16 | 15 | 0.041* | 21 | 21 | 11 | 10 | 6 | 0.000* |
Anal irritation | 22 | 20 | 13 | 9 | 6 | 0.005* | 23 | 18 | 10 | 6 | 5 | 0.008* |
Anal discharge | 13 | 11 | 8 | 7 | 4 | 0.000* | 13 | 6 | 5 | 4 | 2 | 0.220 |
Anal discomfort | 25 | 24 | 19 | 15 | 13 | 0.000* | 22 | 17 | 12 | 8 | 7 | 0.000* |
Complication | ||||||||||||
Diarrhoea | 10 | 6 | 4 | 2 | 2 | 0.011* | 12 | 4 | 3 | 1 | 0 | 0.009* |
Nausea | 9 | 2 | 0 | 0 | 0 | 0.024* | 10 | 3 | 1 | 1 | 0 | 0.029* |
Vomiting | 5 | 0 | 0 | 0 | 0 | 0.560 | 4 | 2 | 1 | 1 | 0 | 0.630 |
Skin rash | 12 | 5 | 2 | 2 | 1 | 0.270 | 9 | 3 | 2 | 0 | 0 | 0.067 |
Pruritus | 13 | 7 | 2 | 1 | 1 | 0.210 | 14 | 5 | 4 | 1 | 0 | 0.056 |
Headache | 19 | 3 | 1 | 0 | 0 | 0.004* | 21 | 11 | 3 | 3 | 0 | 0.006* |
Vertigo | 15 | 4 | 1 | 0 | 0 | 0.012* | 18 | 7 | 2 | 1 | 0 | 0.016* |
Number of individuals in case and control groups are 44 and 42, respectively (ntotal=86).
*Significant differences between case and control groups.