Viral response according to lead-in therapy with interferon and season of initiating hepatitis C virus treatment
| Without lead-in Season A | Season B | p Value | Lead-in Season A | Season B | p Value | |
|---|---|---|---|---|---|---|
| Rapid viral response, n (%) | 91 (38.2) | 78 (32) | 0.18 | 8 (4.3) | 4 (1.5) | 0.07 |
| RNA undetectable or VL ≤15 UI at 4 weeks, n (%) | 193 (82.5) | 181 (76) | 0.09 | 19 (10.4) | 11 (4.2) | 0.013 |
| Viral response at 8 weeks, n (%) | 79 (64) | 85 (58.2) | 0.38 | 60 (44.1) | 87 (44.6) | 0.99 |
| VL ≤15 UI at 8 weeks, n (%) | 119 (97) | 137 (94) | 0.39 | 95 (70) | 136 (70) | 0.99 |
| Viral response at 12 weeks, n (%) | 151 (66.6) | 145 (62) | 0.83 | 94 (56.3) | 126 (54) | 0.74 |
| VL ≤15 UI at 12 weeks, n (%) | 215 (94) | 213 (91.4) | 0.48 | 135 (81) | 200 (85.5) | 0.86 |
| Sustained viral response, n (%) | 147 (74.2) | 147 (72) | 0.57 | 78 (60) | 96 (57.5) | 0.72 |
HCV, hepatitis C virus; VL, viral load.