Table 1

Study procedures

Clinical data collectedBlood samples
Date of birthFBC
Age at time of assessmentLiver enzymes (albumin, bilirubin, ALT, ALP)
Sex at birthAST
EthnicityGGT
WeightHbA1c
HeightFIB-4 score
BMILipids
Waist and Hip circumferenceELF
Blood pressurePRO-C3
AUDIT score33Blood for storage to assess future novel biomarkers of liver disease
Current alcohol consumption (average units/week over last year)
History of previous heavy alcohol consumption (>35 U/week for females or >50 U/week for males) for >1 year
Smoking history
Relevant medical history including:
hypertension, T2DM, dyslipidaemia, obstructive sleep apnoea
Current medications
EQ-5D-L questionnaire34
  • ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUDIT, Alcohol Use Disorders Identification Tool; ELF, enhanced liver fibrosis test; EQ-5D-L, EuroQol-5 Dimensions-Level; FBC, full blood count; GGT, gamma glutamyl transferase; T2DM, type 2 diabetes.