Characteristic | Overall interval | Overall interval | Overall interval | |||||||
Doctor interval | System interval | Diagnostic interval | Treatment interval | |||||||
Median difference (N=4982) | P-value | Median difference (N=5113) | P-value | Median difference (N=4926) | P-value | Median difference (N=5174) | P-value | Median difference (N=4982) | P-value | |
Age (increase in 5 years) | −3 (−6.5 to 0.5) | 0.098 | 0 (−0.3 to 0.4) | 0.969 | −0.7 (−3 to 1.6) | 0.536 | −3.5 (−6.4 to −0.6) | 0.017 | 2 (1.4 to 2.5) | <0.001 |
Sex | ||||||||||
Male | Ref | Ref | Ref | Ref | Ref | |||||
Female | 26.5 (18.9 to 34.2) | <0.001 | 0.7 (−0.2 to 1.7) | 0.138 | 20.2 (14.6 to 25.8) | <0.001 | 27.2 (20.2 to 34.3) | <0.001 | 1.6 (0.3 to 3) | 0.021 |
ON−Marg Summary Score (increase in one point) | 3.7 (−0.7 to 8.1) | 0.096 | −0.3 (−0.7 to 0.2) | 0.21 | 3 (−0.7 to 6.7) | 0.115 | 5 (0.6 to 9.4) | 0.024 | −0.1 (−1.1 to 0.9) | 0.873 |
Disease site | ||||||||||
Proximal colon | Ref | Ref | Ref | Ref | Ref | |||||
Sigmoid and rectosigmoid | 14.3 (5.6 to 23) | 0.001 | 1.4 (0.3 to 2.5) | 0.016 | 8.5 (1.6 to 15.4) | 0.015 | 5.4 (−2.5 to 13.4) | 0.18 | 8.3 (6.5 to 10.2) | <0.001 |
Rectum | 22.1 (13.2 to 30.9) | <0.001 | 4.9 (3.6 to 6.3) | <0.001 | 13.1 (6.3 to 19.8) | <0.001 | 5.5 (−2.6 to 13.5) | 0.184 | 19.6 (17.9 to 21.4) | <0.001 |
Stage | ||||||||||
I | Ref | Ref | Ref | Ref | Ref | |||||
II | −34.3 (−48.1 to −20.4) | <0.001 | −7.3 (−9.1 to −5.4) | <0.001 | −30 (−39.4 to −20.5) | <0.001 | −26.1 (−38.6 to −13.5) | <0.001 | −11.1 (−13.9 to −8.2) | <0.001 |
III | −41.7 (−54.1 to −29.3) | <0.001 | −5.9 (−8 to −3.9) | <0.001 | −30.7 (−39.6 to −21.9) | <0.001 | −35.2 (−45.7 to −24.7) | <0.001 | −12.6 (−15.2 to −10) | <0.001 |
IV | −61.3 (−72.5 to −50.2) | <0.001 | −7.8 (−9.3 to −6.3) | <0.001 | −45.7 (−54.6 to −36.8) | <0.001 | −54.6 (−65.7 to −43.5) | <0.001 | −15 (−17.6 to −12.5) | <0.001 |
Use of lower GI endoscopy in patient LHIN (increase in 1000 procedures per 100 000 residents per year) | −7.6 (−13.8 to −1.4) | 0.017 | 0.4 (−0.4 to 1.2) | 0.328 | −7.6 (−13.1 to −2.1) | 0.007 | −7.3 (−14.3 to −0.3) | 0.041 | −1 (−2.5 to 0.5) | 0.172 |
Year of diagnosis (increase in 1 year) | 0.3 (−1 to 1.6) | 0.629 | −0.2 (−0.3 to 0) | 0.046 | 0.7 (−0.3 to 1.8) | 0.159 | −0.2 (−1.6 to 1.1) | 0.723 | 0.6 (0.3 to 0.9) | <0.001 |
Effect estimates are presented as median days with 95% CIs.
Models are adjusted for age, sex, ON-Marg score, disease site, access to lower endoscopy, year of diagnosis, density of specialists and stage (diagnoses in 2007 and later).
GI, gastrointestinal; LHIN, local health integration network.