Study design and treatment schedule
| Group | No of mice | Test substance | Dose (mg/kg) | Volume (mL/kg) | Regimen | Sacrifice |
| 1 | 8 | Vehicle | – | 5 | PO, QD, 6–9 weeks | 9 weeks |
| 2 | 8 | AFO-202 Beta Glucan | 1 | 5 | PO, QD, 6–9 weeks | 9 weeks |
| 3 | 8 | N-163 Beta Glucan | 1 | 5 | PO, QD, 6–9 weeks | 9 weeks |
| 4 | 8 | AFO-202 Beta Glucan N-163 Beta Glucan | 1 1 | 5 | PO, QD, 6–9 weeks | 9 weeks |
| 5 | 8 | Telmisartan | 10 | 5 | PO, QD, 6–9 weeks | 9 weeks |
PO, per os; QD, every day.