Current sociodemographic and clinical characteristics of 180 adult patients with childhood coeliac disease diagnosis with and without self-reported persistent symptoms while on a strict gluten-free diet
| Persistent symptoms in adulthood | P value | ||||
| Yes, n=33 | No, n=147 | ||||
| Median | Q1, Q3 | Median | Q1, Q3 | ||
| Age, years | 31.6 | 21.1, 45.5 | 26.5 | 22.1, 35.8 | 0.417 |
| Time from diagnosis, years | 20.9 | 12.5, 34.3 | 16.8 | 12.2, 27.0 | 0.250 |
| Body mass index, kg/m2 | 24.4 | 22.0, 26.6 | 22.9 | 21.2, 26.3 | 0.210 |
| n | % | n | % | ||
| Sociodemographic characteristics | |||||
| Working full-time or part-time* | 20 | 83 | 88 | 77 | 0.507 |
| Student | 13 | 39 | 50 | 34 | 0.558 |
| Offspring | 17 | 52 | 60 | 41 | 0.275 |
| Coeliac disease in the family | 21 | 66 | 90 | 62 | 0.707 |
| Health behaviour | |||||
| Member of coeliac society | 18 | 55 | 79 | 55 | 0.995 |
| Current or previous smoking | 12 | 36 | 40 | 27 | 0.306 |
| Regular physical exercise | 27 | 84 | 133 | 92 | 0.198 |
| Use of gluten-free oats | 29 | 88 | 138 | 95 | 0.124 |
| Follow-up of coeliac disease | 6 | 18 | 43 | 29 | 0.197 |
| Comorbidities | |||||
| Allergy† | 13 | 41 | 60 | 41 | 0.937 |
| Asthma | 3 | 9 | 16 | 11 | 1.000 |
| Autoimmune thyroidal disease | 3 | 9 | 12 | 8 | 1.000 |
| Depression | 4 | 12 | 16 | 11 | 1.000 |
| Gastrointestinal disease‡ | 6 | 19 | 8 | 6 | 0.023 |
| Malignancy§ | 0 | 0 | 3 | 2 | 1.000 |
| Osteoporosis/osteopenia | 0 | 0 | 4 | 3 | 1.000 |
| Rheumatic disease | 1 | 3 | 7 | 5 | 1.000 |
| Skin disease¶ | 5 | 16 | 23 | 16 | 0.993 |
| Type I diabetes | 1 | 3 | 8 | 6 | 1.000 |
*Data available for >95% of patients except in 138.
†For example, for pollen, animals, antibiotics, food.
‡For example, peptic ulcer, inflammatory bowel disease, irritable bowel syndrome, gastritis.
§For example, breast cancer and non-Hodgkins lymphoma.
¶For example, atopic dermatitis.
Q1 and Q3, lower and upper quartiles.