Table 1

Clinical characteristics at the time of childhood coeliac disease diagnosis in 180 currently adult patients on a strict gluten-free diet with and without persistent symptoms

	Persistent symptoms in adulthood				P value
	Yes, n=33		No, n=147
	Median	Q₁, Q₃	Median	Q₁, Q₃
Age, years	10.1	4.8, 14.2	9.5	5.8, 13.6	0.716
Year of diagnosis	1995	1982, 2004	1999	1987, 2004	0.270
Haemoglobin, g/L	123	117, 131	124	113, 132	0.677
EmA/ARA§, titre	1:500	1:100, 1:2000	1:200	1:100, 1:1000	0.131
TGA, U/mL	86	26, 120	76	33, 120	0.876
	n	%	n	%
Girls	24	73	101	69	0.651
Main clinical presentation					0.905
Screen-detected	6	18	28	19
Gastrointestinal	19	58	78	53
Extra-intestinal	8	24	40	27
Severity of symptoms‡					0.851
None	8	30	33	30
Mild	11	41	39	35
Moderate or severe	8	30	38	35
Specific symptoms
Abdominal pain	10	37	59	48	0.302
Anaemia	13	41	40	29	0.200
Arthralgia*	1	5	6	7	1.000
Constipation	3	10	11	9	0.733
Diarrhoea	14	47	58	46	0.950
Poor growth	15	47	62	47	0.992
Skin symptoms†	2	10	8	8	0.677
Vomiting	2	7	13	10	0.737
Degree of villous atrophy					0.330
Partial	8	30	39	29
Subtotal	8	30	57	43
Total	11	41	37	28
Type 1 diabetes	0	0	8	7	0.356

*Data available for >80% of patients except in: 112.
†Data available for >80% of patients except in: 124.
‡Data available for >80% of patients except in: 137.
§Data available for >80% of patients except in: 130.
ARA, serum antireticulin antibodies; EmA, serum endomysium antibodies; Q₁ and Q₃, lower and upper quartiles; TGA, tissue transglutaminase antibodies.