Table 1

Univariable and multivariable analyses of factors related to ALT >40 U/L (N=6677)

ParametersUnivariable analysisMultivariable analysis
OR95% CIP valueOR95% CIP value
Male7.66 to 9.6<0.0014.23.3 to 5.5<0.001
Age ≤40 years1.11 to 1.260.062.11.8 to 2.4<0.001
BMI ≥23 kg/m24.343.8 to 5<0.0012.11.8 to 2.45<0.001
Systolic BP ≥130 mm Hg2.22 to 2.5<0.0011.090.9 to 1.260.28
Diastolic BP ≥85 mm Hg2.32.1 to 2.6<0.0011.361.2 to 1.6<0.001
Fasting glucose ≥5.6 mmol/L1.751.5 to 2<0.0011.130.97 to 1.320.12
Cholesterol ≥5.2 mmol/L1.971.75 to 2.2<0.0011.361.18 to 1.56<0.001
Low HDL-C1.121 to 1.260.0531.020.9 to 1.170.78
Triglycerides ≥1.7 mmol/L3.332.94 to 3.76<0.0011.651.4 to 1.9<0.001
Fatty liver on abdominal ultrasound4.43.9 to 5<0.0012.742.4 to 3.2<0.001
HBsAg positivity1.41.16 to 1.68<0.0011.581.3 to 1.95<0.001
Anti-HCV positivity1.550.95 to 2.50.0791.721 to 2.950.051
  • ALT, alanine aminotransferase; BMI, body mass index; BP, blood pressure; HBsAg, hepatitis B antigen surface; HCV, hepatitis C virus; HDL-C, high-density lipoprotein cholesterol.