Selected serum miRNAs for discrimination between AIH and PBC
| Discovery set | Test set | ||||
| CV score | AUC | 95% CI | AUC | 95% CI | |
| Elevated in AIH | |||||
| miR-3665 | 0.91 | 0.94 | 0.88 to 1.00 | 0.38 | 0.02 to 0.73 |
| miR-8072 | 0.86 | 0.95 | 0.89 to 1.00 | 0.53 | 0.18 to 0.87 |
| miR-3196 | 0.84 | 0.95 | 0.89 to 1.00 | 0.90 | 0.70 to 1.00 |
| miR-6125 | 0.84 | 0.91 | 0.82 to 1.00 | 0.90 | 0.73 to 1.00 |
| miR-6836–3 p | 0.82 | 0.90 | 0.80 to 0.99 | 0.38 | 0.03 to 0.73 |
| miR-1908–5 p | 0.82 | 0.86 | 0.73 to 0.98 | 0.70 | 0.35 to 1.00 |
| miR-6729–5 p | 0.82 | 0.90 | 0.81 to 0.99 | 0.80 | 0.52 to 1.00 |
| miR-4725–3 p | 0.82 | 0.91 | 0.83 to 1.00 | 0.88 | 0.65 to 1.00 |
| miR-6789–5 p | 0.82 | 0.92 | 0.84 to 1.00 | 0.78 | 0.51 to 1.00 |
| miR-4634 | 0.82 | 0.91 | 0.82 to 1.00 | 0.98 | 0.90 to 1.00 |
| Elevated in PBC | |||||
| miR-4655–5 p | 0.82 | 0.82 | 0.68 to 0.95 | 0.80 | 0.45 to 1.00 |
Bold indicates the AUC values of miRNAs extracted in the test set.
AIH, autoimmune hepatitis; AUC, area under the curve; CV, cross-validation; PBC, primary biliary cholangitis.; .