Table 1

Previous studies which specifically investigated the impact of stent presence on staging

AuthorsYearEUS typeCancer locationStent, n (type)Comments
Cannon et al,29 N=501998RadialAmpulla25 (PS)Overall accuracy 78%. T staging reduced from 84% to 72% by stent. All patients underwent surgery.
Fusaroli et al,14 N=652006RadialHead of pancreas19 (PS)T stage correct in 85% unstented and 47% with stents. Patients with stents 6.55 times more likely to be incorrectly T staged. All patients underwent surgery.
Bao et al,13 N=762007LinearHead of pancreas36 (not stated)Overall sensitivity 57%, specificity 67%, PPV 61% and NPV 63% for EUS assessment of venous involvement in determining positive resection margin or locally advanced and unresectable at surgery. In 27 patients without stent, were 79%, 69%, 73% and 75% respectively.
Shami et al,15 N=552008LinearPancreas28 (SEMS)Overall staging not just T or vascular stage assessed. EUS correctly staged 52% of patients without SEMS compared with 46% of patients with SEMS. Surgical exploration in 65% and resection in 25% of patients. Main reason for inaccurate staging was failure to identify metastatic disease.
  • EUS, endoscopic ultrasound; NPV, negative predictive value; PPV, positive predictive value; PS, plastic stent; SEMS, self-expandable metal stents.