Summary of the comparison studies of dedicated endoscopy versus non-dedicated endoscopy for Barrett’s surveillance including expert centres versusnon-expert centres
| Study | Study design | Dedicated service | Sites | Participants/ sample size (n) | Study duration | Dysplasia detection rate | Seattle protocol adherence | Prague classification/ delineation | Appropriate scheduling of follow-up | Notes |
| Ooi et al, full paper24 | Prospective dedicated service data Retrospective non-dedicated data, cohort | Endoscopists performed who had prior training in Prague classification, Seattle protocol and lesion recognition | Multicentre: one tertiary referral centre and one community | n=729 | Data between 2007 and 2012 | LGD, HGD, OAC, 18% in dedicated vs 8% in non-dedicated p≤0.0001 | Significantly higher in dedicated | Significantly higher in dedicated lists | Prospective versus retrospective, (selection bias) and retrospective data predates the BSG guideline | |
| Britton et al, full paper25 | Prospective cohort dedicated versus non-dedicated | Single endoscopist who had special interest (clinical fellow) | Single centre | Dedicated, n=217 Non-dedicated, n=78 | Prospective, January 2016–July 2017 Retrospective, November 2013–June 2016 | 4.3% vs 2.6% (p=0.41) | 72% vs 42% vs 50% (p<0.0001) | 100% vs 87.3% vs 82.5% (p<0.0001) | 100% vs 75% (p=<0.0001) | Single centre, not randomised, single endoscopist in the dedicated arm |
| Schölvinck et al, full paper26 | Retrospective cohort of patients with known dysplasia | Expert Barrett’s centre | Expert centre versus community centre outcomes of repeat OGD (Oesophagogastroduodenoscopy) | n=198 | 5 years (January 2008–December 2013) | Visible lesion detection 87% in expert, 60% in community (p≤0.001) | n/a | n/a | n/a | Known dysplasia from prior biopsies selection bias |
| Cameron et al, full paper27 | Prospective cohort comparing to referring centres outcomes | Tertiary referral centre | Single specialist centre | n=69 | 3 years (November 2008–September 2011) | 56% increased cancer detection (p=0.036) | Seattle protocol adherence in original centre 20% | n/a | n/a | Reassessing known dysplastic cases, predates many guidelines |
n/a, not applicable.