Table 4

Fasting and postprandial hormone profiles

HormoneBaselineTreatmentEffectP value
Total GLP-1Fasting value
(pmol/L)
9 (4,16)11 (5, 34)0 (−5, 30)0.345
AUC
(h×pmol/L)
67 (28, 90)71 (46, 117)20 (−20, 31)0.063
Intact GLP-2Fasting value
(pmol/L)
15 (9, 22)16 (10, 53)1 (−2, 32)0.201
AUC
(h×pmol/L)
75 (47, 103)125 (89, 184)49 (39, 105)0.018
Total PYYFasting value
(pmol/L)
25 (6, 83)25 (6, 85)0 (−56, 19)0.686
AUC
(h×pmol/L)
212 (30, 432)146 (70, 293)25 (−227, 79)0.612
Total GIPFasting value
(pmol/L)
5 (1, 8)3 (1, 6)−2 (−4, 4)0.288
AUC
(h×pmol/L)
158 (17, 204)99 (28, 190)−44 (61, 37)0.091
GlucagonFasting value
(pmol/L)
7 (3, 12)6 (2, 15)−1 (−7, 7)0.389
AUC
(h×pmol/L)
29 (16, 46)25 (18, 33)−1 (−17, 4)0.398
  • Data are presented as median (min, max).

  • AUC, area under the curve; GIP, glucose-dependent insulinotropic peptide; GLP, glucagon like peptide; PYY, peptide YY.