Table 4

Laboratory data in both groups before ttt and at end of ttt

		SOF LED	SOF DACLA	P value
		N=51	N=77	P value
Uric acid before ttt	Mean±SD	4.9±1.2	4.6±1.08	0.1135
	Median	5	4.1
	IQR	4–6	4–5
Uric acid end of ttt	Mean±SD	6.1±3.1	5.6±2.6	0.100
	Median	5	4.8
	IQR	4.5–6	4–5.5
ALT before ttt	Median	53	58	0.170
ALT before ttt	IQR	47–65	47–74	0.170
ALT end of ttt	Median	28	28	0.119
ALT end of ttt	IQR	25–29	26–30	0.119
AST before ttt	Median	59	67	0.053
AST before ttt	IQR	49–75	53.5–86	0.053
AST end of ttt	Median	31	34	0.055
AST end of ttt	IQR	28–33	29.5–37.5	0.055
Creatinine before ttt	Mean±SD	0.98±0.21	0.95±0.19	0.320
	Median	1	0.9
	IQR	0.8–1.1	0.8–1
Creatinine end of ttt	Mean±SD	1.12±0.61	1.11±0.56	0.649
	Median	1	1
	IQR	0.9–1.1	0.9–1
Platelets before ttt	Median	101	110	0.063
Platelets before ttt	IQR	87–123	95.5–126	0.063
Platelets end of ttt	Median	104	115	0.093
Platelets end of ttt	IQR	87–130	94–129	0.093
Bilirubin before ttt	Median	1.1	1.2	0.982
Bilirubin before ttt	IQR	0.9–1.3	0.9–1.4
Bilirubin end of ttt	Median	1.09	1.2	0.082
Bilirubin end of ttt	IQR	0.9–1.2	0.9–1.35	0.082
Albumin before ttt	Median	3.7	3.6	0.566
Albumin before ttt	IQR	3.5–4.2	3.4–3.8	0.566
Albumin end of ttt	Median	3.7	3.6	0.256
Albumin end of ttt	IQR	3.4–4.2	3.4–3.9	0.256
INR before ttt	Range	1–1.8	1–1.7	0.096
INR before ttt	Mean±SD	1.2±0.2	1.3±0.2	0.096
INR end of ttt	Range	1–1.7	1–1.6	0.078
INR end of ttt	Mean±SD	1.2±0.3	1.2±0.2	0.078

Independent samples t-test for parametric quantitative data between the two groups.
Mann Whitney test for non-parametric quantitative data between the two groups.
Significant level at italics p value <0.05.
ALT, alanine transaminase; AST, aspartate transaminase; DACLA, daclatsvir; INR, international normalised ratio; LED, ledipasvir; SOF, sofosbuvir; ttt, treatment.