Table 1

Concordance between select ICD-10-AM codes for cirrhosis or cirrhosis-related complications and medical chart review

ICD-10-AM coden with condition on clinical reviewn with codePPV
(95% CI)
NPV
(95% CI)
κ
Cirrhosis413
K70.3 Alcoholic cirrhosis of liver1930.97 (0.95 to 0.99)0.35 (0.30 to 0.40)
K74.4 Secondary biliary cirrhosis*121.000.24 (0.21 to 0.28)
K74.5 Biliary cirrhosis, unspecified60.67 (0.28 to 0.94)0.23 (0.20 to 0.27)
K74.6 Other and unspecified cirrhosis of liver1690.96 (0.93 to 0.99)0.33 (0.28 to 0.38)
Grouped† K70.3, K74.4, K74.5, K74.6 (Algorithm #1)3490.96 (0.94 to 0.98)0.60 (0.53 to 0.67)0.606
Cirrhosis-related complications
 HCCC22.0 Liver cell carcinoma82740.97 (0.92 to 1.00)0.98 (0.96 to 0.99)0.910
 AscitesR18 Ascites2441550.97 (0.94 to 0.99)0.76 (0.71 to 0.80)0.625
 VaricesGrouped† varices (I85.0, I85.9, I86.4, I98.2, I98.3)2431570.95 (0.91 to 0.98)0.76 (0.71 to 0.80)0.606
I85.0 Oesophageal varices with bleeding271.000.58 (0.54 to 0.62)
I85.9 Oesophageal varices without bleeding320.88 (0.73 to 0.96)0.58 (0.53 to 0.62)
I86.4 Gastric varices410.93 (0.82 to 0.98)0.59 (0.55 to 0.63)
I98.2 Oesophageal varices without bleeding in diseases classified elsewhere520.94 (0.86 to 0.99)0.60 (0.56 to 0.65)
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere431.000.60 (0.55 to 0.64)
 SBPGrouped† SBP (K65.0, K65.9)46470.75 (0.61 to 0.85)0.98 (0.96 to 0.99)0.729
K65.0 Acute peritonitis240.63 (0.43 to 0.80)0.94 (0.92 to 0.96)
K65.9 Peritonitis, unspecified230.87 (0.70 to 0.97)0.95 (0.93 to 0.97)
 HEGrouped† HE (G31.2, G93.4)142640.55 (0.43 to 0.67)0.78 (0.74 to 0.81)0.211
G31.2 Degeneration of nervous system due to alcohol300.37 (0.21 to 0.55)0.74 (0.70 to 0.78)
G93.4 Encephalopathy, unspecified340.71 (0.54 to 0.84)0.77 (0.73 to 0.80)
  • *ICD-10-AM code for primary biliary cirrhosis/cholangitis (K74.3) not shown as this code may be associated with early stage liver disease, not cirrhosis

  • †‘Grouped’ codes indicate the presence of ≥1 code during an encounter.

  • HCC, hepatocellular carcinoma; HE, hepatic encephalopathy; ICD-10-AM, Australian Modification of the 10th revision of the International Classification of Diseases; NPV, negative predictive value; PPV, positive predictive value; SBP, spontaneous bacterial peritonitis.