Summary of studies comparing EUS-BD to ERCP in malignant biliary obstruction
| Author (year) | Study design | Total no subjects | Type of EUS-BD | Type of stent used | Technical success EUS versus ERCP rate, % (n=#) | Clinical success EUS versus ERCP rate, % (n=#) | Total Adverse Events EUS-BD versus ERCP rate, % (n=#) |
| Tonozuka72 (2013) | Single Centre, Retrospective | 11 (8 EUS-BD; 3 ERCP) | EUS-CDS EUS-HGS EUS‐CAS | FCSEMS | 100 (8/8) vs 100 (3/3) | 100 (8/8) vs 100 (3/3) | 37.5 (3/8) vs 0 |
| Hamada78 (2014) | Multicentre, Retrospective | 20 (7 EUS-BD; 13 ERCP) | EUS-CDS EUS-HGS | SEMS Plastic | — | — | 14 (1/7) vs 7.6 (1/13) |
| Dhir77 (2015) | Multicentre, Retrospective | 208 (104 EUS-BD;104 ERCP) | EUS-CDS EUS-AG | FCSEMS UCSEMS | 93.3 (97/104) vs 94.2 (98/104) | 89.4 (93/104) vs 91.3 (95/104) | 8.7 (9/104) vs 8.7 (9/104) |
| Kawakubo80 (2016) | Single Centre, Retrospective | 82 (26 EUS-BD; 56 ERCP) | EUS-CDS | PCSEMS | - | 96.2 (25/26) vs 98.2 (55/56) | 26.9 (7/26) vs 35.7 (20/56) |
| Bang75 (2018) | Single Centre, Prospective, RCT | 67 (33 EUS-BD; 34 ERCP) | EUS-CDS | FCSEMS | 90.9 (30/33) vs 94.1 (32/34) | 97 (32/33) vs 91 (31/34) | 21.2 (7/33) vs 14.7 (5/34) |
| Hamada79 (2018) | Multicentre, Retrospective | 110 (20 EUS; 90 ERCP) | EUS-CDS EUS-HGS | FCSEMS PCSEMS UCSEMS | - | - | 35% (7/20) vs 8.8% (8/90) |
| Paik73 (2018) | Multicentre, Prospective, RCT | 125 (64 EUS-BD; 61 ERCP) | EUS-CDS EUS-HGS | Hybrid PCSEMS | 93.8 (60/64) vs 90.2 (55/61) | 90 (54/60) vs 94.5 (52/55) | 10.9 (7/64) vs 39 (24/61) |
| Park74 (2018) | Single Centre, Prospective, RCT | 28 (14 EUS-BD; 14 ERCP) | EUS-CDS | PCSEMS | 92.8 (13/14) vs 100 (14/14) | 92.8 (13/14) vs 100 (14/14) | 0 vs 0 |
| Yamao82 (2018) | Multicentre, Retrospective | 39 (14 EUS-BD; 25 ERCP) | EUS-CDS EUS-HGS | FCSEMS PCSEMS Plastic | 100 (14/14) vs 56 (14/25) | 92.9 (13/14) vs 52 (13/25) | 57 (8/14) vs 32 (8/25) |
| Nakai81 (2019) | Multicentre, Prospective | 59 (34 EUS-BD; 25 ERCP) | EUS-CDS | FCSEMS PCSEMS | 97 (33/34) | 100 (34/34) | 15 (5/34) |
ERCP, endoscopic retrograde cholangiopancreatography; EUS-AG, EUS-guided antegrade stenting; EUS-BD, endoscopic ultrasound-guided biliary drainage; EUS-CAS, EUS‐guided choledochoantrostomy; EUS-CDS, EUS-guided choledochoduodenostomy; EUS-HGS, EUS-guided hepaticogastrostomy; FCSEMS, fully covered SEMS; PCSEMS, partially covered SEMS; RCT, randomised controlled trial; SEMS, self-expanding metal stents; UCSEMS, uncovered SEMS.