Table 4

Sex-specific association of cirrhosis status by quintile of AFB1-lysine adduct levels

AFB1-albumin adductsRange
(pg/mg albumin)
CasesControlsCrude modelAdjusted model*
OR95% CIOR95% CI
Female
 Quintile 10.77–2.404301.001.00
 Quintile 22.42–4.369252.700.74 to 9.822.310.52 to 10.27
 Quintile 34.47–7.7711243.440.97 to 12.162.020.44 to 9.31
 Quintile 47.83–13.9712224.091.16 to 14.393.950.96 to 16.35
 Quintile 514.62–137.4216186.661.93 to 23.075.611.24 to 25.38
P value for trend0.0020.014
Male
 Quintile 10.49–3.153221.001.00
 Quintile 23.42–6.594221.330.27 to 6.672.850.36 to 22.41
 Quintile 36.76–12.2012146.291.50 to 26.3124.853.10 to 199.00
 Quintile 412.49–29.60161011.732.77 to 49.6225.443.26 to 198.64
 Quintile 529.98–171.5812136.771.61 to 28.549.641.21 to 76.94
P value for trend<0.0010.010
  • *Adjusted for ethnicity, HBV status, and heavy alcohol consumption.

  • AFB1, aflatoxin B1; HBV, hepatitis B virus.