Association of cirrhosis status by quintile of AFB1-lysine adduct levels
| AFB1-albumin adducts | Range (pg/mg albumin) | Cases | Controls | Crude model | Adjusted model* | ||
| OR | 95% CI | OR | 95% CI | ||||
| Quintile 1 | 0.49–2.68 | 5 | 54 | 1.00 | – | 1.00 | – |
| Quintile 2 | 2.75–4.98 | 15 | 45 | 3.60 | 1.21 to 10.67 | 4.92 | 1.32 to 18.35 |
| Quintile 3 | 5.07–9.58 | 21 | 39 | 5.82 | 2.02 to 16.76 | 4.85 | 1.31 to 17.88 |
| Quintile 4 | 9.66–19.66 | 27 | 33 | 8.84 | 3.10 to 25.20 | 12.01 | 3.34 to 43.14 |
| Quintile 5 | 19.68–171.58 | 31 | 29 | 11.55 | 4.05 to 32.89 | 12.41 | 3.23 to 47.74 |
| P value for trend | 0.001 | 0.001 | |||||
Interaction terms were included for the covariates; only AFB1 and sex were statistically significant (p=0.01).
*Adjusted for sex, ethnicity, HBV status, and heavy alcohol consumption.
AFB1, aflatoxin B1; HBV, hepatitis B virus.