Cox proportional hazards for incident colorectal cancer
| Colorectal caner (case/n) | Model 1 | Model 2 | |||
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| VAI | – | – | – | – | |
| The lowest tertile | 23/9307 | 1.00 (reference) | – | 1.00 (reference) | – |
| The middle tertile | 33/9303 | 1.30 (0.76 to 2.28) | 0.338 | 1.14 (0.65 to 1.99) | 0.646 |
| The highest tertile | 60/3903 | 2.41 (1.50 to 4.02) | <0.001 | 1.78 (1.05 to 3.02) | 0.032 |
| Men | 1.41 (0.81 to 2.45) | 0.220 | |||
| Age, years | 1.07 (1.05 to 1.09) | <0.001 | |||
| Non-smoker | 1.00 (reference) | – | |||
| Ex-smoker | 1.43 (0.81 to 2.52) | 0.213 | |||
| Current smoker | 1.49 (0.85 to 2.62) | 0.167 | |||
| Non-alcohol consumer | 1.00 (reference) | – | |||
| Light alcohol consumer | 1.37 (0.80 to 2.33) | 0.253 | |||
| Moderate alcohol consumer | 1.80 (0.99 to 3.25) | 0.052 | |||
| Heavy alcohol consumer | 2.42 (1.34 to 4.35) | 0.003 | |||
| Non-regular exerciser | 1.00 (reference) | – | |||
| Regular exerciser | 0.82 (0.74 to 2.01) | 0.446 | |||
| SBP, mm Hg | 0.99 (0.99 to 1.01) | 0.892 | |||
Exercise was defined as non-regular exerciser (0) or regular exerciser (1), smoking status was defined as non-smoker (0), ex-smoker (1) or current smoker (2), and alcohol consumption was defined as no or minimal alcohol consumer (0), light alcohol consumer (1), moderate alcohol consumer (2) and heavy alcohol consumer (3). Model 1 was unadjusted. Model 2 was adjusted for sex, age, smoking status, alcohol consumption, exercise and systolic blood pressure (SBP).
VAI, Visceral Adiposity Index.